72987

2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose

≥97% (HPLC)

• Sinonimo/i: 2-NBDG, 2-[N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino]-2-deoxy-D-glucose
• Formula empirica (notazione di Hill): C₁₂H₁₄N₄O₈
• Numero CAS: 186689-07-6
• Peso molecolare: 342.26
• Beilstein: 7603370
• Numero MDL: MFCD23135882
• Codice UNSPSC: 12352108
• ID PubChem: 329764517
• NACRES: NA.32

Proprietà

• Origine biologica: synthetic
• Saggio: ≥97% (HPLC)
• Forma fisica: powder
• Fluorescenza: λ_ex 494 nm; λ_em 551 nm in DMSO
• applicazioni: cell analysis
• Temperatura di conservazione: −20°C
• Stringa SMILE: OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](Nc1ccc([N+]([O-])=O)c2nonc12)C=O
• InChI: 1S/C12H14N4O8/c17-3-6(11(20)12(21)8(19)4-18)13-5-1-2-7(16(22)23)10-9(5)14-24-15-10/h1-3,6,8,11-13,18-21H,4H2/t6-,8+,11+,12+/m0/s1; QUTFFEUUGHUPQC-ILWYWAAHSA-N

Descrizione

Descrizione generale

2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl) amino]-D-glucose, also known as 2-NBDG, is a fluorescent D-glucose analog. The consequent fluorescent activity is detected by flow cytometry. 2-NBDG is incubated directly with the test sample for uptake, followed by measurement.

Applicazioni

2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl) amino]-D-glucose is used as a fluorescent indicator for direct glucose uptake measurement. 2-NBDG is used as a fluorescent deoxyglucose analog to study the tumor cells. For in vivo imaging of epileptic activity experiments, 2-NBDG is used as a fluorescent deoxyglucose analog.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable