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46041

Sigma-Aldrich

Esterase basic kit

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About This Item

Numero CAS:
53-41-8
Numero CE:
232-773-7
Numero MDL:
MFCD00003618
Codice UNSPSC:
12352204
ID PubChem:
329757070

Temperatura di conservazione

−20°C

Stringa SMILE

C[C@]12CC[C@@H](O)C[C@@H]1CC[C@@H]3[C@@H]2CC[C@@]4(C)[C@H]3CCC4=O

InChI

1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12-16,20H,3-11H2,1-2H3/t12-,13+,14-,15-,16-,18-,19-/m0/s1
QGXBDMJGAMFCBF-HLUDHZFRSA-N

Componenti

Composition:
96667 Esterase from Bacillus subtilis, 10 mg
51963 Esterase from Bacillus subtilis, 10 mg
46051 Esterase from Bacillus stearothermophilus, 10 mg
79208 Esterase from Rhizopus oryzae, 100 mg
46056 Esterase from Candida lipolytica, 50 mg
46059 Esterase from Mucor miehei, 50 mg
46069 Esterase from horse liver, 50 mg
46071 Esterase from Saccharomyces cerevisiae, 25 mg
46058 Esterase from hog liver, 10 mg
75742 Esterase Pseudomonas fluorescens, recombinant from E. coli, 10 mg

Pittogrammi

Health hazard
GHS08

Avvertenze

Danger

Indicazioni di pericolo

H334

Consigli di prudenza

P261 - P284 - P501

Classi di pericolo

Resp. Sens. 1

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

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Certificati d'analisi (COA)

Lot/Batch Number
1421158

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Jamie B Scaglione et al.
Journal of medicinal chemistry, 51(5), 1309-1318 (2008-02-16)
Although the structural features of binding sites for neuroactive steroids on gamma-aminobutryic acid type A (GABA A) receptors are still largely unknown, structure-activity studies have established a pharmacophore for potent enhancement of GABA A receptor function by neuroactive steroids. This
Bryson W Katona et al.
European journal of medicinal chemistry, 43(1), 107-113 (2007-04-17)
Allopregnanolone (1) and pregnanolone (2), steroids containing a 17beta-acetyl group, are potent enhancers of GABA (gamma-aminobutyric acid) action at GABAA receptors. Their effects are enantioselective with the non-naturally occurring enantiomers (ent-1 and ent-2) being less potent. Androsterone (3) and etiocholanolone
Jamie B Scaglione et al.
Journal of medicinal chemistry, 49(15), 4595-4605 (2006-07-21)
Benz[f]indenes are tricyclic compounds with a linear 6-6-5 fused carbocyclic ring system. When properly substituted, benz[f]indenes can satisfy the pharmacophore requirements of the critical hydrogen-bond donor and acceptor groups found in neuroactive steroids that modulate gamma-aminobutyric acidA (GABAA) receptor function.
Edith Bellavance et al.
Journal of medicinal chemistry, 52(23), 7488-7502 (2009-09-24)
17beta-Hydroxysteroid dehydrogenase type 7 (17beta-HSD7) catalyzes the reduction of estrone (E(1)) into estradiol (E(2)) and of dihydrotestosterone (DHT) into 5alpha-androstane-3beta,17beta-diol (3beta-diol), therefore modulating the level of mitogenic estrogens and androgens in humans. By classical and parallel chemistry, we generated several
Hiroyuki Sato et al.
Journal of medicinal chemistry, 51(6), 1831-1841 (2008-03-01)
TGR5, a metabotropic receptor that is G-protein-coupled to the induction of adenylate cyclase, has been recognized as the molecular link connecting bile acids to the control of energy and glucose homeostasis. With the aim of disclosing novel selective modulators of
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