PHR1366

Dibutilftalato

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinonimo/i: n-butil ftalato, DBP, Estere dibutilico dell’acido ftalico
• Formula condensata: C₆H₄-1,2-[CO₂(CH₂)₃CH₃]₂
• Numero CAS: 84-74-2
• Peso molecolare: 278.34
• Beilstein: 1914064
• Numero CE: 201-557-4
• Numero MDL: MFCD00009441
• Codice UNSPSC: 41116107
• ID PubChem: 329823345
• NACRES: NA.24

Proprietà

• Grado: certified reference material; pharmaceutical secondary standard
• Livello qualitativo: 300
• agenzia: traceable to Ph. Eur. D1010000; traceable to USP 1187080
• Densità del vapore: 9.6 (vs air)
• Tensione di vapore: 1 mmHg ( 147 °C)
• Famiglia di API: dibutyl phthalate
• CdA: current certificate can be downloaded
• Temp. autoaccensione: 756 °F
• Limite di esplosione: 0.47 %, 236 °F
• Confezionamento: pkg of 1 g
• tecniche: HPLC: suitable; gas chromatography (GC): suitable
• Indice di rifrazione: n20/D 1.492 (lit.)
• P. ebollizione: 340 °C (lit.)
• Punto di fusione: −35 °C (lit.)
• Densità: 1.043 g/mL at 25 °C (lit.)
• applicazioni: pharmaceutical (small molecule)
• Formato: neat
• Temperatura di conservazione: 2-30°C
• Stringa SMILE: CCCCOC(=O)c1ccccc1C(=O)OCCCC
• InChI: 1S/C16H22O4/c1-3-5-11-19-15(17)13-9-7-8-10-14(13)16(18)20-12-6-4-2/h7-10H,3-6,11-12H2,1-2H3; DOIRQSBPFJWKBE-UHFFFAOYSA-N

Descrizione

Descrizione generale

Dibutyl Phthalate is a diester of phthalate, commonly synthesized by the condensation of the carboxy groups of phthalic acid with two molecules of 1-butanol.[1] It is used as a plasticizer and film coating agent in solid pharmaceutical dosage forms.[2]
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Applicazioni

Plastificante

Dibutyl Phthalate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and dietary supplements by chromatography.[2][3][4]

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Risultati analitici

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Altre note

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota a piè di pagina

To see an example of a Certificate of Analysis for this material enter LRAA1470 in the slot below. This is an example certificate only and may not be the lot that you receive.

Informazioni sulla sicurezza

• Pittogrammi: GHS08,GHS09
• Avvertenze: Danger
• Indicazioni di pericolo: H360FD,H410
• Consigli di prudenza: P202 - P273 - P280 - P308 + P313 - P391 - P405
• Classi di pericolo: Aquatic Acute 1 - Aquatic Chronic 2 - Repr. 1B
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): 339.8 °F
• Punto d’infiammabilità (°C): 171 °C