Passa al contenuto
Merck
Tutte le immagini(1)

Documenti fondamentali

PHR1095

Supelco

Caffeina

Pharmaceutical Secondary Standard; Certified Reference Material

Sinonimo/i:

1,3,7-trimetilxantina

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali


About This Item

Formula empirica (notazione di Hill):
C8H10N4O2
Numero CAS:
Peso molecolare:
194.19
Beilstein:
17705
Numero CE:
Numero MDL:
Codice UNSPSC:
12352210
ID PubChem:
NACRES:
NA.24

Grado

certified reference material
pharmaceutical secondary standard

Livello qualitativo

agenzia

traceable to USP 1086006

Famiglia di API

caffeine

CdA

current certificate can be downloaded

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Punto di fusione

~Approximately 237 °C
234-236.5 °C (lit.)

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-30°C

Stringa SMILE

CN1C(=O)N(C)c2ncn(C)c2C1=O

InChI

1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3
RYYVLZVUVIJVGH-UHFFFAOYSA-N

Informazioni sul gene

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Descrizione generale

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Caffeine is mainly used as a diuretic and as a stimulant to central nervous system, heart rate, and respiration.

Applicazioni

Caffeine may be used as a reference standard for the determination of the analyte in pharmaceutical formulations by high-performance liquid chromatography and spectrophotometry.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Risultati analitici

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Altre note

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota a piè di pagina

To see an example of a Certificate of Analysis for this material enter LRAC3327 in the slot below. This is an example certificate only and may not be the lot that you receive.

Prodotti consigliati

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Slide 1 of 8

1 of 8

Caffeina traceable to primary standards (LGC)

Supelco

75035

Caffeina

Caffeina phyproof® Reference Substance

PHL89591

Caffeina

Vanillina Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1245

Vanillina

L-Lysine Acetate Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1096

L-Lysine Acetate

Caffeina certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Supelco

56396

Caffeina

Simultaneous spectrophotometric determination of paracetamol and caffeine in tablet formulation.
Vichare V, et al.
International Journal of PharmTech Research, 2(4), 2512-2516 (2010)
Development and validation of a simple RP-HPLC method for determination of caffeine in pharmaceutical dosage forms.
Chowdhury SR, et al.
Asian Journal of Pharmaceutical Analysis, 2(1), 1-4 (2012)
Jonathan M Hodgson et al.
The American journal of clinical nutrition, 97(5), 943-950 (2013-04-05)
Measures of blood pressure variation have been associated with cardiovascular disease and related outcomes. The regular consumption of black tea can lower blood pressure, but its effects on blood pressure variation have yet to be investigated. We aimed to assess
Nicolas Bousette et al.
Journal of cellular physiology, 229(3), 374-383 (2013-09-17)
Calnexin (CNX) is an endoplasmic reticulum (ER) quality control chaperone that has been implicated in ER stress. ER stress is a prominent pathological feature of various pathologic conditions, including cardiovascular diseases. However, the role of CNX and ER stress has
Pierre Ayotte et al.
Environmental health perspectives, 113(10), 1318-1324 (2005-10-06)
The Lower North Shore region of the St. Lawrence River is home to a fish-eating population that displays an unusually high body burden of several organochlorines, including polychlorinated biphenyls (PCBs) and dioxin-like compounds (DLCs). We measured biomarkers indicative of liver

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.