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P0250000

Pancuronium bromide

European Pharmacopoeia (EP) Reference Standard

Sinonimo/i:

1,1′-[(2β,3α,5α,16β,17β)-3,17-bis(Acetyloxy)androstane-2,16-diyl]bis(1-methylpiperidinium) dibromide

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About This Item

Formula empirica (notazione di Hill):
C35H60Br2N2O4
Numero CAS:
15500-66-0
Peso molecolare:
732.67
Beilstein:
4226892
Numero MDL:
MFCD00079223
Codice UNSPSC:
41116107
ID PubChem:
329820026
NACRES:
NA.24

Grado

pharmaceutical primary standard

Famiglia di API

pancuronium 

Produttore/marchio commerciale

EDQM

applicazioni

pharmaceutical (small molecule)

Formato

neat

Stringa SMILE

[Br-].[Br-].[H][C@@]12CC[C@]3([H])[C@]([H])(CC[C@]4(C)[C@@H](OC(C)=O)[C@H](C[C@@]34[H])[N+]5(C)CCCCC5)[C@@]1(C)C[C@@H]([C@H](C2)OC(C)=O)[N+]6(C)CCCCC6

InChI

1S/C35H60N2O4.2BrH/c1-24(38)40-32-21-26-13-14-27-28(35(26,4)23-31(32)37(6)19-11-8-12-20-37)15-16-34(3)29(27)22-30(33(34)41-25(2)39)36(5)17-9-7-10-18-36;;/h26-33H,7-23H2,1-6H3;2*1H/q+2;;/p-2/t26-,27+,28-,29-,30-,31-,32-,33-,34-,35-;;/m0../s1
NPIJXCQZLFKBMV-YTGGZNJNSA-L

Informazioni sul gene

human ... CHRNA1(1134) , CHRNB1(1140) , CHRND(1144) , CHRNE(1145) , CHRNG(1146)

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Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Pancuronium bromide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

Pittogrammi

Skull and crossbones
GHS06

Avvertenze

Danger

Indicazioni di pericolo

H301

Consigli di prudenza

P301 + P330 + P331 + P310

Classi di pericolo

Acute Tox. 3 Oral

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number

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M F Roizen et al.
Annals of internal medicine, 88(1), 64-68 (1978-01-01)
Pancuronium bromide is a nondepolarizing muscle relaxant approved to induce skeletal muscle relaxation during anesthesia and to facilitate the management of patients undergoing mechanical ventilation. The use of pancuronium bromide during surgery led to the appreciation that it has advantages
Alina Teliban et al.
Journal of neurophysiology, 111(10), 2071-2083 (2014-02-28)
Intact and injured cutaneous C-fibers in the rat sural nerve are cold sensitive, heat sensitive, and/or mechanosensitive. Cold-sensitive fibers are either low-threshold type 1 cold sensitive or high-threshold type 2 cold sensitive. The hypothesis was tested, in intact and injured
J Simoes et al.
Journal of perinatology : official journal of the California Perinatal Association, 9(2), 215-218 (1989-06-01)
Nursing care of the newborn in respiratory distress has become highly sophisticated and technical, requiring skill in principles of neonatal assessment and therapeutic interventions. It is important to be knowledgeable about the technical aspects of the equipment and monitors. However
Pancuronium bromide: a review of its pharmacological properties and clinical application.
T M Speight et al.
Drugs, 4(3), 163-226 (1972-01-01)
F Bolzoni et al.
The Journal of physiology, 593(4), 947-966 (2014-11-25)
Trans-spinal DC stimulation affects both postsynaptic neurons and the presynaptic axons providing input to these neurons. In the present study, we show that intraspinally applied cathodal current replicates the effects of trans-spinal direct current stimulation in deeply anaesthetized animals and
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