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C2174000

Cilazapril

European Pharmacopoeia (EP) Reference Standard

Sinonimo/i:

Cilazapril monohydrate

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About This Item

Formula empirica (notazione di Hill):
C22H31N3O5 · H2O
Numero CAS:
92077-78-6
Peso molecolare:
435.51
Numero MDL:
MFCD01692810
Codice UNSPSC:
41116107
NACRES:
NA.24

Grado

pharmaceutical primary standard

Famiglia di API

cilazapril

Produttore/marchio commerciale

EDQM

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

N21N(CCC[C@H]2C(=O)O)CCC[C@@H](C1=O)N[C@@H](CCc3ccccc3)C(=O)OCC.O

InChI

1S/C22H31N3O5.H2O/c1-2-30-22(29)18(13-12-16-8-4-3-5-9-16)23-17-10-6-14-24-15-7-11-19(21(27)28)25(24)20(17)26;/h3-5,8-9,17-19,23H,2,6-7,10-15H2,1H3,(H,27,28);1H2/t17-,18-,19-;/m0./s1
JQRZBPFGBRIWSN-YOTVLOEGSA-N

Categorie correlate

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Cilazapril EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

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Vojnosanitetski pregled, 66(11), 904-908 (2009-12-19)
Poisoning caused by drugs with cardiodepressive effects is an urgent condition in medicine which is associated with high mortality rate regardless of modern therapeutic methods. Accidental or intentional poisoning whit these drugs produces heart activity depression and cardiovascular collapse as
Spironolactone attenuates oxidative stress in patients with chronic kidney disease.
Marcin Renke et al.
Hypertension (Dallas, Tex. : 1979), 52(5), e132-e133 (2008-10-01)
Shih-Hsien Sung et al.
Journal of the Chinese Medical Association : JCMA, 71(5), 247-253 (2008-05-21)
Combined regimen may be superior to monotherapy in blood pressure (BP) control. Since BP control is critically related to cardiovascular mortality and morbidity in hypertensive patients, this study aimed to evaluate the efficacy and safety of a low-dose combined regimen
How controlling of hypertension might matter.
Kazuo Hara et al.
Circulation journal : official journal of the Japanese Circulation Society, 73(12), 2208-2209 (2009-11-27)
Nikola Radović et al.
Croatian medical journal, 49(5), 600-607 (2008-10-18)
To investigate the effects of angiotensin-converting enzyme inhibitor (cilazapril) and angiotensin II type I receptor antagonist (losartan) on tubular and interstitial cell apoptosis and caspase-3 activity in rats with obstructive nephropathy after unilateral ureteral obstruction. Rats with unilateral obstructive nephropathy
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