A0200000

Acetylsalicylic acid

European Pharmacopoeia (EP) Reference Standard

• Sinonimo/i: 2-Acetoxybenzoic acid, O-Acetylsalicylic acid, ASA, Aspirin
• Formula condensata: 2-(CH₃CO₂)C₆H₄CO₂H
• Numero CAS: 50-78-2
• Peso molecolare: 180.16
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329770581
• MDL number: MFCD00002430
• Beilstein/REAXYS Number: 779271

Proprietà

• grade: pharmaceutical primary standard
• API family: aspirin
• manufacturer/tradename: EDQM
• mp: 134-136 °C (lit.)
• application(s): pharmaceutical; pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: CC(=O)Oc1ccccc1C(O)=O
• InChI: 1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
• InChI key: BSYNRYMUTXBXSQ-UHFFFAOYSA-N
• Gene Information: human ... PTGS1(5742), PTGS2(5743)

Descrizione

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Acetylsalicylic acid EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Blocks the production of prostaglandins by inhibiting cyclooxygenase (prostaglandin H synthase), with greater selectivity toward the COX-1 isoform. The antithrombotic effect is due to the inhibition of COX-1 in platelets that blocks thromboxane production and platelet aggregation. Chemopreventive against colorectal and other solid tumors.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Parola di avvertenza: Warning
• Classe di stoccaggio: 11 - Combustible Solids
• Che succede?: WGK 1
• Punto di infiammabilità (°F): 482.0 °F
• Punto di infiammabilità (°C): 250 °C
• Codici di pericolo: H302,H412
• Avvertenze di sicurezza: P264 - P270 - P273 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 3