95197
Kojic acid
analytical standard
Sinonimo/i:
2-Hydroxymethyl-5-hydroxy-γ-pyrone, 5-Hydroxy-2-hydroxymethyl-4H-4-pyranone
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100 MG
CHF 77.80
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100 MG
CHF 77.80
About This Item
Formula empirica (notazione di Hill):
C6H6O4
Numero CAS:
Peso molecolare:
142.11
Beilstein:
120895
Numero CE:
Numero MDL:
Codice UNSPSC:
85151701
ID PubChem:
NACRES:
NA.24
Prodotti consigliati
Grado
analytical standard
Livello qualitativo
Saggio
≥99.0% (HPLC)
Durata
limited shelf life, expiry date on the label
tecniche
HPLC: suitable
gas chromatography (GC): suitable
Punto di fusione
152-155 °C (lit.)
applicazioni
cleaning products
cosmetics
food and beverages
personal care
Formato
neat
Stringa SMILE
OCC1=CC(=O)C(O)=CO1
InChI
1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2
BEJNERDRQOWKJM-UHFFFAOYSA-N
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Descrizione generale
Kojic acid, a tyrosinase inhibitor, is produced by several fungi species, including Aspergillus oryzae.[1] It exhibits skin-lightening property, due to its ability to chelate the copper-containing enzyme tyrosinase in the formation of melanin.[2] Kojic acid is also commonly used as a whitening agent in regular cosmetics, bleaching cosmetics, etc.[3] It is found to be a therapeutic agent and helps in preventing pigmentation.[3]
Applicazioni
Kojic acid may be used as an analytical reference standard for the determination of the analyte in skin whitening cosmetics[2][1] and bleaching cosmetics[3] using high performance liquid chromatography with UV detection (HPLC-UV).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Azioni biochim/fisiol
Tyrosinase inhibitor.
Prodotti consigliati
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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I clienti hanno visto anche
Simultaneous determination of magnesium ascorbyl phosphate, ascorbyl glucoside, kojic acid, arbutin and hydroquinone in skin whitening cosmetics by HPLC
Huang C-S, et al.
Journal of food and drug analysis, 12(1) (2004)
Combining high-performance liquid chromatography with on-line microdialysis sampling for the simultaneous determination of ascorbyl glucoside, kojic acid, and niacinamide in bleaching cosmetics.
Lin CH et al
Analytica Chimica Acta, 581(1), 102-107 (2007)
Min Hi Park et al.
Archives of pharmacal research, 38(4), 505-511 (2014-12-17)
Tyrosinase inhibitors might have potential use in cosmetic and medicinal products for the prevention of pigmentation disorders. However, only a few inhibitors are currently used due to their cytotoxicity, and lack of selectivity and stability. In this study, we synthesized
Atsushi Yoshimori et al.
Bioorganic & medicinal chemistry, 22(21), 6193-6200 (2014-10-08)
Tyrosinase inhibitors have become increasingly critical agents in cosmetic, agricultural, and medicinal products. Although a large number of tyrosinase inhibitors have been reported, almost all the inhibitors were unfortunately evaluated by using commercial available mushroom tyrosinase. Here, we examined the
Quantitative determination of $\alpha$-arbutin, $\beta$-arbutin, kojic acid, nicotinamide, hydroquinone, resorcinol, 4-methoxyphenol, 4-ethoxyphenol, and ascorbic acid from skin whitening products by HPLC-UV
Wang YH, et al.
Journal of AOAC (Association of Official Analytical Chemists) International, 98(1), 5-12 (2015)
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