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90834

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Bradykinin

analytical standard

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About This Item

Formula empirica (notazione di Hill):
C50H73N15O11 · xC2H4O2
Numero CAS:
Peso molecolare:
1060.21 (free base basis)
Numero CE:
Codice UNSPSC:
85151701
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

Saggio

≥98.0% (HPLC)

Durata

limited shelf life, expiry date on the label

Classi chimiche degli analiti

peptides

tecniche

HPLC: suitable

Impurezze

≤10 wt. % water

Colore

white

applicazioni

food and beverages

Formato

neat

Temperatura di conservazione

2-8°C

InChI

1S/C50H73N15O11/c51-32(16-7-21-56-49(52)53)45(72)65-25-11-20-39(65)47(74)64-24-9-18-37(64)43(70)58-28-40(67)59-34(26-30-12-3-1-4-13-30)41(68)62-36(29-66)46(73)63-23-10-19-38(63)44(71)61-35(27-31-14-5-2-6-15-31)42(69)60-33(48(75)76)17-8-22-57-50(54)55/h1-6,12-15,32-39,66H,7-11,16-29,51H2,(H,58,70)(H,59,67)(H,60,69)(H,61,71)(H,62,68)(H,75,76)(H4,52,53,56)(H4,54,55,57)/t32-,33-,34-,35-,36-,37-,38-,39-/m0/s1
QXZGBUJJYSLZLT-FDISYFBBSA-N

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Amino Acid Sequence

Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg

Applicazioni

Bradykinin acetate salt may be used as a precursor for the preparation of bradykinin (BK) prior to its determination from acidic aqueous solutions by electromembrane extraction (EME) followed by analysis using high performance liquid chromatography (HPLC) with ultraviolet (UV) detector.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Azioni biochim/fisiol

Bradykinin is a pro-inflammatory peptide that acts through G-protein-coupled receptors. It activates sphingolipid metabolism. Fibroblasts treated with bradykinin produce a rapid and important increase in ceramide which is followed by a transient rise in sphingosine content. The peptide also increases ceramide cellular content by rapidly mobilizing neutral glycolipids. Bradykinin plays an important role in the regulation of fluid and electrolyte balance, smooth muscle contraction, vasodilation and capillary permeability. The bradykinin potentiators, which possess no bradykinin activity themselves, enhance the activity of bradykinin.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Electromembrane extraction of peptides-Fundamental studies on the supported liquid membrane.
Seip KF, et al.
Journal of Separation Science, 34(23), 3410-3417 (2011)

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