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791962

Sigma-Aldrich

Cyclopentyl methyl ether

greener alternative

inhibitor-free, anhydrous, ≥99.9%

Sinonimo/i:

CMPE, CPME

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About This Item

Formula empirica (notazione di Hill):
C6H12O
Numero CAS:
5614-37-9
Peso molecolare:
100.16
Numero MDL:
MFCD08276401
Codice UNSPSC:
12352112
ID PubChem:
329768304
NACRES:
NA.21

Grado

anhydrous

Livello qualitativo

100

Saggio

≥99.9%

Forma fisica

liquid

Caratteristiche più verdi

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

Impurezze

≤0.0050% water
water

P. eboll.

106 °C/760 mmHg

Punto di fusione

-140 °C (lit.)

Densità

0.86 g/mL at 25 °C

Categoria alternativa più verde

, Aligned

Stringa SMILE

COC1CCCC1

InChI

1S/C6H12O/c1-7-6-4-2-3-5-6/h6H,2-5H2,1H3
SKTCDJAMAYNROS-UHFFFAOYSA-N

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Categorie correlate

Descrizione generale

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. Cyclopentyl methyl ether (CPME) is a greener alternative to other ethereal solvents such as tetrahydrofuran (THF), 2-methyl tetrahydrofuran (2-MeTHF), dioxane (carcinogenic), tert-Butyl methyl ether (MTBE), and 1,2-dimethoxyethane (DME) and thus has been enhanced for "Safer Solvents and Auxiliaries". Click here for more information.

Applicazioni

  • Cyclopentyl methyl ether (CPME) is an alternative to ether solvents such as THF, diethyl ether, and MTBE with a higher resistance to peroxide formation.
  • The more environmentally conservative CPME solvent replaces hazardous solvents in order to achieve sustainability and reduce environmental and operational costs.
  • CPME offers considerable potential and advantage as a direct replacement for CH2Cl2 in binary eluents using MeOH as the modifier with MeOH–DMC and i-PrOH–EtOAc.

Caratteristiche e vantaggi

Greener alternative for THF, diethyl ether, and MTBE

Altre note

The Toxicological Assessment of Cyclopentyl Methyl Ether (CPME) as a Green Solvent

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

Pittogrammi

FlameExclamation mark
GHS02,GHS07

Avvertenze

Danger

Indicazioni di pericolo

H225,H302,H315,H319

Classi di pericolo

Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

<37.4 °F - closed cup

Punto d’infiammabilità (°C)

< 3 °C - closed cup

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Certificati d'analisi (COA)

Lot/Batch Number
SHBQ6771
SHBQ8311
SHBQ3729
SHBP8687
SHBP4327

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Watanabe, K.;
Organic Process Research & Development, 11 (2007)
MacMillan, D. S. ;
Green Chemistry (2012)
Rikako Takahiro et al.
Biological & pharmaceutical bulletin, 38(1), 58-65 (2015-03-07)
The aim of this study was to characterize the kinetics of metabolite formation of the phosphodiesterase type-5 (PDE5) inhibitors sildenafil and tadalafil by CYP3A4, CYP3A5, and CYP3A7 isoforms. The formations of N-desmethyl sildenafil and desmethylene tadalafil were examined using CYP3A

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