MABX1911

Anti-human IgM (10mg) KC

from mouse

• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: mouse
• Forma dell’anticorpo: purified antibody
• Tipo di anticorpo: secondary antibodies
• Clone: monoclonal
• Reattività contro le specie: human
• tecniche: ELISA: suitable; immunodiffusion: suitable
• Isotipo: IgG1

Descrizione

Descrizione generale

Secondary antibody specific for Human Immunoglobulin M
Immunoglobulin M (IgM) is a highly conserved antibody in vertebrates and is expressed early during development of immune system.[1] It is present as a pentamer in the serum and is secreted by peritoneal B cells.[2]

Specificità

Specific for Human IgM. No cross reactivity with human IgA, IgD, IgE or IgG.

Immunogeno

corresponding to Human Human Serum IgM.

Applicazioni

Detect Human Serum IgM using this mouse monoclonal, Cat. No. MABX1911-10KC, validated for use in and ELISA and Lateral Flow Assay.

None

Research Category
Secondary & Control Antibodies

Azioni biochim/fisiol

Immunoglobulin M (IgM) plays a key role in engulfing the apoptotic cells. The reduction in serum IgM levels leads to increased autoimmune response and a higher risk of infections. IgM exhibits polyreactive and autoreactive functionality.[2] A defect in IgM production is observed in X-linked agammaglobulinemia.[3]

Qualità

Tested

Stato fisico

Format: Purified

Ion-exchange chromatography

Purified mouse monoclonal in buffer containing 50 mM NaCl, 10 mM PBS, pH 8.0, 0.1 % sodium azide (NaN₃).

Stoccaggio e stabilità

2-8°C. For long-term storage, freeze at -20°C.

Altre note

Concentration: Please refer to lot specific datasheet.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.