MAB3310
Anti-TIMP-2 Antibody, clone 67-4H11
clone 67-4H11, Chemicon®, from mouse
Sinonimo/i:
Tissue Inhibitor of Metalloproteinase-2
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About This Item
Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Prodotti consigliati
Origine biologica
mouse
Livello qualitativo
Forma dell’anticorpo
purified immunoglobulin
Tipo di anticorpo
primary antibodies
Clone
67-4H11, monoclonal
Reattività contro le specie
rabbit, goat, guinea pig, rat, human, bovine, mouse
Produttore/marchio commerciale
Chemicon®
tecniche
ELISA: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable
Isotipo
IgG1κ
N° accesso NCBI
N° accesso UniProt
Condizioni di spedizione
dry ice
modifica post-traduzionali bersaglio
unmodified
Informazioni sul gene
human ... TIMP2(7077)
Specificità
The antibody specifically reacts with human TIMP-2.
SPECIES REACTIVITY:
Cross-reacts with mouse, rat, guinea pig, rabbit and bovine TIMP-2.
SPECIES REACTIVITY:
Cross-reacts with mouse, rat, guinea pig, rabbit and bovine TIMP-2.
Immunogeno
Synthetic peptide corresponding to amino acids 178-193 of human TIMP-2 (numbered from the propeptide)
YRGAAPPKQEFLDIED
YRGAAPPKQEFLDIED
Applicazioni
Anti-TIMP-2 Antibody, clone 67-4H11 detects level of TIMP-2 & has been published & validated for use in ELISA, WB, IH(P).
Immunoblotting
Immunohistochemistry on paraffin-embedded, PLP fixed tissue at 5 μg/mL (see Tomita reference) or frozen tissues at 1 μg/mL (see Ohashi reference).
ElA
Immunohistochemistry on paraffin-embedded, PLP fixed tissue at 5 μg/mL (see Tomita reference) or frozen tissues at 1 μg/mL (see Ohashi reference).
ElA
Research Category
Cell Structure
Cell Structure
Research Sub Category
MMPs & TIMPs
MMPs & TIMPs
Linkage
Replaces: MAB3356
Stato fisico
Format: Purified
Liquid in 0.1M Na-Phosphate buffer, pH 7.0 containing 2% protease free bovine serum albumin.
Stoccaggio e stabilità
Maintain frozen at -20°C in undiluted aliquots for up to 12 months.
Altre note
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Note legali
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Esclusione di responsabilità
Manufactured by Daiichi Fine Chemical Co., Ltd
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Codice della classe di stoccaggio
12 - Non Combustible Liquids
Classe di pericolosità dell'acqua (WGK)
WGK 2
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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Wenni Tong et al.
Developmental neurobiology, 70(3), 182-194 (2009-12-18)
A recent study has shown that increased activity of matrix metalloproteinases-2 and metalloproteinases-9 (MMP-2 and MMP-9) has detrimental effect on the brain after neonatal hypoxia. The present study determined the effect of maternal hypoxia on neuronal survivability and the activity
TNF-alpha stimulates activation of pro-MMP2 in human skin through NF-(kappa)B mediated induction of MT1-MMP.
Han, YP; Tuan, TL; Wu, H; Hughes, M; Garner, WL
Journal of Cell Science null
John Ng et al.
Investigative ophthalmology & visual science, 49(12), 5295-5306 (2008-07-22)
Ocular surface squamous neoplasia (OSSN) is an uncommon tumor of the corneal and conjunctival epithelium associated with risk of permanent visual impairment. The purposes of this study were to (1) identify and localize potential mediators in tissue from patients with
Oliver Galm et al.
Oncogene, 24(30), 4799-4805 (2005-05-05)
The tissue inhibitor of metalloproteinases-2 (TIMP-2) is known to antagonize matrix metalloproteinase activity and to suppress tumor growth, angiogenesis, invasion and metastasis. We analysed the methylation status of the CpG island in the TIMP-2 promoter region by methylation-specific polymerase chain
Tao Xu et al.
Experimental and therapeutic medicine, 10(2), 683-688 (2015-12-02)
The mortality rates associated with colorectal cancer (CRC) are high due to metastasis. Epithelial-to-mesenchymal transition (EMT) is a key step in tumor metastasis. The aim of the present study was to investigate the function of microRNA-20a (miR-20a) in EMT. The
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