582235

Tetanus Toxin, C-Fragment, Clostridium tetani

The C-terminal binding portion of the heavy chain of tetanus toxin.

• Codice UNSPSC: 12352200
• NACRES: NA.77

Proprietà

• Livello qualitativo: 100
• Forma fisica: lyophilized
• Produttore/marchio commerciale: Calbiochem^®
• Condizioni di stoccaggio: OK to freeze
• Solubilità: sterile distilled water: soluble
• Condizioni di spedizione: ambient
• Temperatura di conservazione: 2-8°C

Descrizione

Descrizione generale

Caution: may contain trace amounts of intact toxin.

The C-terminal binding portion of the chain of tetanus toxin. The intact toxin is known to block neurotransmitter release at inhibitory synapses in cultured spinal cord cells. Shows trans-synaptic retrograde transport in the central nervous system. Caution: may contain trace amounts of intact toxin. Follow the handling procedure described in the information that accompanies the product.

The C-terminal binding portion of the heavy chain of tetanus toxin.

The C-terminal binding portion of the heavy chain of tetanus toxin. Useful for binding studies.

Azioni biochim/fisiol

Primary Target
Useful for binding studies

Product does not compete with ATP.

Attenzione

Toxicity: Highly Toxic (H)

Stato fisico

Lyophilized from 10 mM sodium phosphate buffer, pH 7.5.

Ricostituzione

Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Once an aliquot has been thawed, do not refreeze. Aqueous stock solutions are stable for 7-10 days at 4°C.

Risultati analitici

Single major band by SDS-PAGE

Altre note

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Poulain, B. 1994. Pathol. Biol. 42, 173.
Williamson, L.C., et. al. 1993. Soc. Neurosci. 19, Abstract 770.10.
Evinger, C. and Erichsen, J.T. 1986. Brain Res.380, 383.
Helting, T.B. and Zwisler, O. 1977. J. Biol. Chem.252, 187.
Matsuda, M. and Yoneda, M. 1977. Biochem. Biophys. Res. Commun.77, 268.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3