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Documenti

07-181

Sigma-Aldrich

Anti-AMPK α-pan Antibody

Upstate®, from rabbit

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

rabbit

Forma dell’anticorpo

affinity purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Purificato mediante

affinity chromatography

Reattività contro le specie

human, rat

Produttore/marchio commerciale

Upstate®

tecniche

western blot: suitable

Isotipo

IgG

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

dry ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... PRKAA1(5562)

Specificità

Recognizes AMP-activated protein kinase alpha subunits.

Immunogeno

human AMP-activated protein a1 catalytic subunit (AEKQKHDGRVKIGHYILGD)

Applicazioni

Anti-AMPK α-pan Antibody is an antibody against AMPK α-pan for use in WB.
Research Category
Signaling
Research Sub Category
Insulin/Energy Signaling

Qualità

routinely evaluated by immunoblot on a rat liver protein preparation

Descrizione del bersaglio

63 kDa

Stato fisico

ImmunoAffinity Purified
Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.

Stoccaggio e stabilità

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Risultati analitici

Control
Rat liver preparation

Note legali

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Sandra C Rodrigues et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 307(9), R1146-R1156 (2014-08-29)
The liver plays an essential role in maternal metabolic adaptation during late pregnancy. With regard to lipid metabolism, increased secretion of very low-density lipoprotein (VLDL) is characteristic of late pregnancy. Despite this well-described metabolic plasticity, the molecular changes underlying the
Neuroprotective Effects of AMP-Activated Protein Kinase on Scopolamine Induced Memory Impairment.
Kim, SJ; Lee, JH; Chung, HS; Song, JH; Ha, J; Bae, H
The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology null
Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice.
Lin, J; Wu, PH; Tarr, PT; Lindenberg, KS; St-Pierre, J; Zhang, CY; Mootha, VK; Jager et al.
Cell null
Andreas Buch Møller et al.
Journal of applied physiology (Bethesda, Md. : 1985), 118(8), 971-979 (2015-02-14)
Data from transgenic animal models suggest that exercise-induced autophagy is critical for adaptation to physical training, and that Unc-51 like kinase-1 (ULK1) serves as an important regulator of autophagy. Phosphorylation of ULK1 at Ser(555) stimulates autophagy, whereas phosphorylation at Ser(757)
Inhibition of AMP-activated protein kinase sensitizes cancer cells to cisplatin-induced apoptosis via hyper-induction of p53.
Kim, HS; Hwang, JT; Yun, H; Chi, SG; Lee, SJ; Kang, I; Yoon, KS; Choe, WJ; Kim, SS; Ha, J
The Journal of Biological Chemistry null

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