PRKAA1
protein kinase, AMP-activated, alpha 1 catalytic subunit
Synonyms:
AMPK, AMPKa1
Species:
Human PRKAA1 (5562), Mouse Prkaa1 (105787), Rat Prkaa1 (65248), Horse PRKAA1 (100009710), sheep PRKAA1 (100294665), dog PRKAA1 (479351), domestic guinea pig Prkaa1 (100714483), Zebrafish prkaa1 (100001198), chicken PRKAA1 (427185), cow PRKAA1 (540404) ...More
UniProtKB ID:
Gene ID:
- Human(5562) Summary: The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
- Mouse(105787) protein kinase, AMP-activated, alpha 1 catalytic subunit
- Rat(65248) protein kinase, AMP-activated, alpha 1 catalytic subunit
- Horse(100009710) protein kinase, AMP-activated, alpha 1 catalytic subunit
- sheep(100294665) protein kinase, AMP-activated, alpha 1 catalytic subunit
- dog(479351) protein kinase, AMP-activated, alpha 1 catalytic subunit
- domestic guinea pig(100714483) protein kinase, AMP-activated, alpha 1 catalytic subunit
- Zebrafish(100001198) protein kinase, AMP-activated, alpha 1 catalytic subunit
- chicken(427185) protein kinase, AMP-activated, alpha 1 catalytic subunit
- cow(540404) protein kinase, AMP-activated, alpha 1 catalytic subunit
- naked mole-rat(101722998) protein kinase, AMP-activated, alpha 1 catalytic subunit
- sheep(101103425) protein kinase, AMP-activated, alpha 1 catalytic subunit
- domestic cat(101095885) protein kinase, AMP-activated, alpha 1 catalytic subunit
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Phospho-PRKAA1-T183/PRKAA2-T172 antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
western blot
Anti-Phospho-PRKAA1-T183/PRKAA2-T172 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Phospho-PRKAA1-T183/PRKAA2-T172 antibody produced in rabbit, ,
Species Reactivity
human, rat
Application
western blot
Anti-AMPK alpha Antibody, clone 2D22, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Phospho-AMPKα1-S485 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Proteins
Product Number
Description
Species
AMPK (α1/β2/γ1), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
AMPK (α1/β1/γ3), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
AMPK (α1/β1/γ1), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human