999992P

16:0 Diether PC

Avanti Research^™ - A Croda Brand 999992P, powder

• Sinonimo/i: 1,2-di-O-hexadecyl-sn-glycero-3-phosphocholine
• Formula empirica (notazione di Hill): C₄₀H₈₄NO₆P
• Numero CAS: 36314-47-3
• Peso molecolare: 706.07
• Numero MDL: MFCD00066564
• Codice UNSPSC: 51191904
• NACRES: NA.25

Proprietà

• Stato: powder
• Confezionamento: pkg of 1 × 10 mg (999992P-10mg)
• Produttore/marchio commerciale: Avanti Research^™ - A Croda Brand 999992P
• Tipo di lipide: phospholipids; cardiolipins
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• Stringa SMILE: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCCCCCCCCCCCCCCC)COCCCCCCCCCCCCCCCC)=O
• InChI: 1S/C40H84NO6P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-35-44-38-40(39-47-48(42,43)46-37-34-41(3,4)5)45-36-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h40H,6-39H2,1-5H3; MWTIGLPPQBNUFP-UHFFFAOYSA-N

Descrizione

Descrizione generale

16:0 Diether PC (phosphocholine) is a zwitterionic lipid[1] having choline as the alcohol moiety, attached to the phosphate group. It has two hexadecane chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds.[2]

Applicazioni

16:0 Diether PC or 1,2-di-O-hexadecyl-sn-glycero-3-phosphocholine might be used:

• to study the miscibility and phase behavior of the cationic 1,2-dipalmitoyl-sn-glycero-3-ethylphosphocholine (EDPPC)[1]
• in unilamellar vesicles to study glycolipid transfer protein (GLTP)-mediated transfer of anthrylvinyl-galactosylceramide (AV-GalCer) from different ether phospholipid matrices[3]
• as a non-ladderane phosphocholine (PC) lipid reference sample in reversed-phase liquid chromatography (LC) method to separate PC lipids[4]
• to prepare large phospholipid bicelles in order to determine the three-dimensional backbone structure of the transmembrane domain of Vpu from human immunodeficiency virus (HIV)-1 by solid-state nuclear magnetic resonance (NMR) spectroscopy[5]

Azioni biochim/fisiol

Ether glycerolipids serve as membrane molecules and cellular mediators. Ether linked phospholipids act as precursors for important signaling molecules.[6] 16:0 Diether PC (phosphocholine) is known to interdigitate even in the absence of chemical inducers or pressure.[1]

Confezionamento

5 mL Amber Glass Screw Cap Vial (999992P-10mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3