In the powder form, this product is stored at 2-8°C. The material is soluble at 2 mg/mL in DMSO. The stability of this product in solution has not been determined. Other sources indicate that aqueous solutions should be prepared fresh daily. This information has not been validated.
SML2283
Lenalidomide
≥98% (HPLC), powder, cereblon binder
Sinonimo/i:
Lenalidomide, 1-Oxo-4-amino-2-(2,6-dioxopiperidin-3-yl)isoindole, 3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione, 3-(4-Amino-1-oxoisoindolin-2-yl)piperidin-2,6-dione, 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione, CC 5013, CC-5013
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Cambia visualizzazione
| A voi/SKU | Disponibilità | Prezzo |
|---|---|---|
100 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 61.50 |
250 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 140.00 |
Informazioni su questo articolo
Formula empirica (notazione di Hill):
C13H13N3O3
Numero CAS:
Peso molecolare:
259.26
NACRES:
NA.77
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Servizio Tecnico
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Permettici di aiutartiNome del prodotto
Lenalidomide, ≥98% (HPLC)
ligand
lenalidomide
assay
≥98% (HPLC)
form
powder
reaction suitability
reagent type: ligand
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
O=C1N(C2CCC(NC2=O)=O)CC3=C1C=CC=C3N
InChI
1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)
InChI key
GOTYRUGSSMKFNF-UHFFFAOYSA-N
Biochem/physiol Actions
Lenalidomide, a derivative of thalidomide, is an immunomodulatory agent that is approved drug for treatment of multiple myeloma. Apparently Lenalidomide is a ligand of ubiquitin E3 ligase cereblon that induces the enzyme to degrade the Ikaros transcription factors IKAROS family zinc finger 1 (IKZF1) and IKZF3. Lenalidomide possess pleiotropic antitumor effects. It is used in the treatment of 5q-deletion associated myelodysplastic syndrome (del(5q)-MDS).
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Questo articolo | |||
|---|---|---|---|
| form powder | form powder | form powder | form powder |
| assay ≥98% (HPLC) | assay ≥95% | assay ≥98% (HPLC) | assay ≥98% |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. - |
| solubility DMSO: 2 mg/mL, clear | solubility - | solubility DMSO: ≥14 mg/mL | solubility DMSO: 20 mg/mL, clear |
| color white to beige | color - | color yellow | color white |
| ligand lenalidomide | ligand lenalidomide | ligand pomalidomide | ligand thalidomide |
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signalword
Danger
hcodes
Hazard Classifications
Repr. 1B - STOT RE 2
target_organs
Blood
Classe di stoccaggio
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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