810267P
Avanti
C11 TopFluor™ Glucosyl Ceramide
Avanti Research™ - A Croda Brand 810267P, powder
Sinonimo/i:
N-[11-(dipyrrometheneboron difluoride)undecanoyl]-D-glucosyl-β1-1′-D-erythro-sphingosine
Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Scegli un formato
250 μG
CHF 425.00
Scegli un formato
Cambia visualizzazione
250 μG
CHF 425.00
About This Item
Formula empirica (notazione di Hill):
C48H80N3O8F2
Numero CAS:
Peso molecolare:
865.16
Numero MDL:
Codice UNSPSC:
12352211
NACRES:
NA.25
Prodotti consigliati
Saggio
>99% (TLC)
Stato
powder
Confezionamento
pkg of 1 × 250 μg (810267P-250ug)
Produttore/marchio commerciale
Avanti Research™ - A Croda Brand 810267P
Condizioni di spedizione
dry ice
Temperatura di conservazione
−20°C
Descrizione generale
Glucosyl Ceramide (GlcCer)/cerebroside/galactosylceramide is a neutral, polar lipid. It can be ionized delicately in negative-and positive-ion modes.[1] It is the simplest glycosphingolipids (GSLs), that is present abundantly in the mammalian tissues. GlcCer is produced through glycosylation of Cer with the help of GlcCer synthase (GCS) at the cytosolic leaflet of Golgi apparatus.[2]
Applicazioni
C11 TopFluor™ Glucosyl Ceramide is suitable to use as a label in the GLM II model and as a component in the usual giant unilamellar vesicle (GUV) lipid mixture (GLM).[3]
Azioni biochim/fisiol
Glucosyl ceramide (GlcCer) plays a major role in the pathways of glycosphingolipid metabolism. It helps to modulate cell physiology. It acts as an intracellular messenger in cell maintenance and regulation.[2]
Confezionamento
5 mL Amber Glass Screw Cap Vial (810267P-250ug)
Note legali
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
Codice della classe di stoccaggio
11 - Combustible Solids
Scegli una delle versioni più recenti:
Certificati d'analisi (COA)
Lot/Batch Number
It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documenti section.
Se ti serve aiuto, non esitare a contattarci Servizio Clienti
Possiedi già questo prodotto?
I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Characterization of Lipids by Electrospray Ionization Mass Spectrometry, Lipid Analysis
Lipid analysis (2012)
Effect of glucosylceramide on the biophysical properties of fluid membranes
Varela ARP, et al.
Biochimica et Biophysica Acta - Biomembranes, 1828(3), 1122-1130 (2013)
Omid Motabar et al.
Analytical and bioanalytical chemistry, 402(2), 731-739 (2011-10-29)
Glucocerebrosidase is a lysosomal enzyme that catalyzes the hydrolysis of glucosylceramide to form ceramide and glucose. A deficiency of lysosomal glucocerebrosidase due to genetic mutations results in Gaucher disease, in which glucosylceramide accumulates in the lysosomes of certain cell types.
Lipid segregation and membrane budding induced by the peripheral membrane binding protein annexin A2
Drucker P, et al.
Test, 288(34), 24764-24776 (2013)
Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..
Contatta l'Assistenza Tecnica.
