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D80002

DCC

99%

Sinonimo/i:

N,N′-Dicyclohexylcarbodiimide

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Informazioni su questo articolo

Formula condensata:
C6H11N=C=NC6H11
Numero CAS:
Peso molecolare:
206.33
UNSPSC Code:
12352111
NACRES:
NA.22
PubChem Substance ID:
EC Number:
208-704-1
Beilstein/REAXYS Number:
610662
MDL number:
eCl@ss:
32150917
Assay:
99%
Form:
solid
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Quality Segment

assay

99%

form

solid

reaction suitability

reaction type: Coupling Reactions

bp

122-124 °C/6 mmHg (lit.)

mp

34-35 °C (lit.)

SMILES string

C1CCC(CC1)N=C=NC2CCCCC2

InChI

1S/C13H22N2/c1-3-7-12(8-4-1)14-11-15-13-9-5-2-6-10-13/h12-13H,1-10H2

InChI key

QOSSAOTZNIDXMA-UHFFFAOYSA-N

Gene Information

human ... EPHX2(2053)
mouse ... Ephx2(13850)

General description

DCC is the acronym for N,N′-dicyclohexylcarbodiimide. In peptide synthesis, it is utilized for the activation of carboxyl group. The structure of DCC has been analyzed based on IR and Raman spectral data. It mediates the esterification of poly(vinyl alcohol) with free levulinic acid to form poly(vinyl alcohol-co-vinyl levulinate).

Application

DCC has been used in the preparation of titanate nanotubes-phthalocyanine(TiONts-Pc) nanohybrids and 7-((tert-butyldimethylsilyl)oxy)hepta-2,4-diyn-1-yl propynoate.
DCC may be used to promote the esterification of
7-((tert-butyldimethylsilyl)oxy)hepta-2,4-diyn-1-ol with propiolic acid to form 7-((tert-butyldimethylsilyl)oxy)hepta-2,4-diyn-1-yl propynoate.
It can also used to synthesize:
  • 1,3-Thiazetedine derivatives via [2+2] cycloaddition with 2-phenylethenyl- and 2-(4-nitrophenyl)ethenyl isothiocyanates.
  • 1,3,5-Oxadiazine-4-thiones via [4+2] cycloaddition with benzoyl isothiocyanates.
  • Sterically hindered 1,3,4-oxadiazole derivatives by reacting with (N-isocyanimino)triphenylphosphorane in the presence of aromatic (or heteroaromatic) carboxylic acids.

Carboxy group activating reagent for peptide synthesis.

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36650379115SAB2105672
DCC 99%

Sigma-Aldrich

D80002

DCC

DCC puriss., ≥99.0% (GC)

Sigma-Aldrich

36650

DCC

DCC 1.0 M in methylene chloride

Sigma-Aldrich

379115

DCC

description

99%

description

puriss., ≥99.0% (GC)

description

1.0 M in methylene chloride

description

affinity isolated antibody

assay

99%

assay

≥99.0% (GC)

assay

-

assay

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

reaction suitability

reaction type: Coupling Reactions

reaction suitability

reaction type: Coupling Reactions

reaction suitability

reaction type: Coupling Reactions

reaction suitability

-

form

solid

form

solid

form

liquid

form

buffered aqueous solution

mp

34-35 °C (lit.)

mp

32.0-37.0 °C, 34-35 °C (lit.)

mp

-

mp

-

bp

122-124 °C/6 mmHg (lit.)

bp

122-124 °C/6 mmHg (lit.)

bp

-

bp

-


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Pittogrammi

Skull and crossbonesCorrosion

Parola di avvertenza

Danger

Codici di pericolo

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Sens. 1

Che succede?

WGK 3

Punto di infiammabilità (°F)

235.4 °F - closed cup

Punto di infiammabilità (°C)

113 °C - closed cup

DPI (dispositivi di protezione individuale)

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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