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M70800

Sigma-Aldrich

3-Methyl-1-phenyl-2-pyrazoline-5-one

99%, for peptide synthesis

Sinonimo/i:

Edaravone, 5-Methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one

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CHF 13.80
100 G
CHF 27.30
500 G
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5 G
CHF 13.80
100 G
CHF 27.30
500 G
CHF 78.50

About This Item

Formula empirica (notazione di Hill):
C10H10N2O
Numero CAS:
Peso molecolare:
174.20
Beilstein:
609575
Numero CE:
Numero MDL:
Codice UNSPSC:
12352005
ID PubChem:
NACRES:
NA.22

CHF 13.80


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Nome del prodotto

3-Methyl-1-phenyl-2-pyrazoline-5-one, 99%

Livello qualitativo

Saggio

99%

Stato

powder, crystals or chunks

P. ebollizione

287 °C/265 mmHg (lit.)

Punto di fusione

126-128 °C (lit.)

applicazioni

peptide synthesis

Stringa SMILE

CC1=NN(C(=O)C1)c2ccccc2

InChI

1S/C10H10N2O/c1-8-7-10(13)12(11-8)9-5-3-2-4-6-9/h2-6H,7H2,1H3
QELUYTUMUWHWMC-UHFFFAOYSA-N

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Applicazioni

3-Methyl-1-phenyl-2-pyrazoline-5-one may be used:
  • As a reagent for the detection of reducing carbohydrates by ESI/MALDI-MS.[1]
  • To improve the sensitivity of reducing mono- and oligo-saccharides for their subsequent determination using capillary zone electrophoresis.[2]
  • For the precolumn derivatization of the monosaccharide components of Salvia miltiorrhiza, liguspyragine hydrochloride, and glucose injection prior to their analysis by high performance liquid chromatography (HPLC).[3]

Reagent for detection of reducing carbohydrates by ESI/MALDI -MS.[4]

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral - Eye Irrit. 2

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


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Fa-Huan Ge et al.
Journal of analytical methods in chemistry, 2017, 9245620-9245620 (2017-05-11)
Salvia miltiorrhiza, liguspyragine hydrochloride, and glucose injection (SLGI) was made of Salvia miltiorrhiza Bge., liguspyragine hydrochloride, glucose, and glycerin. There were many kinds of monosaccharide components in SLGI, which might be from the raw material and Salvia miltiorrhiza Bge. Separation
Influence of the labeling group on ionization and fragmentation of carbohydrates in mass spectrometry
Lattova E, et al.
Journal of the American Society For Mass Spectrometry, 16(5), 683-696 (2005)
Capillary zone electrophoresis of reducing mono-and oligo-saccharides as the borate complexes of their 3-methyl-1-phenyl-2-pyrazolin-5-one derivatives
Honda S, et al.
Carbohydrate Research, 215(1), 193-198 (1991)
Xin-Gang Du et al.
Journal of natural products, 73(8), 1422-1426 (2010-08-04)
Two new dimeric xanthone O-glycosides, puniceasides A (1) and B (2), a new trimeric O-glycoside, puniceaside C (3), and two new trimeric C-glycosides, puniceasides D (4) and E (5), together with 12 known xanthones were isolated from the entire plant
Hidehiko Nakagawa et al.
Bioorganic & medicinal chemistry letters, 16(23), 5939-5942 (2006-09-26)
We synthesized various 3-methyl-1-phenyl-5-pyrazolone (edaravone) derivatives and evaluated their oxidation potential and hydroxyl radical scavenging activity. It was found 3-methyl-1-(pyridin-2-yl)-5-pyrazolone had a much higher ability to scavenge the radical than did edaravone itself. Its efficient radical scavenging activity was assumed

Articoli

Glycans play a key role in protein structure and disease; representation on cell surfaces is the glycome.

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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