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A10809

Sigma-Aldrich

4′-Hydroxy-3′-methoxyacetophenone

98%

Sinonimo/i:

Acetovanillone, Apocynin

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25 G
CHF 37.70
100 G
CHF 108.00

CHF 37.70

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Cambia visualizzazione
25 G
CHF 37.70
100 G
CHF 108.00

About This Item

Formula condensata:
HOC6H3(OCH3)COCH3
Numero CAS:
498-02-2
Peso molecolare:
166.17
Beilstein:
637373
Numero CE:
207-854-5
Numero MDL:
MFCD00008747
Codice UNSPSC:
12352100
ID PubChem:
24890503
NACRES:
NA.22

CHF 37.70

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Livello qualitativo

100

Saggio

98%

Stato

powder

P. ebollizione

263-265 °C/17 mmHg (lit.)

Punto di fusione

112-115 °C (lit.)

Stringa SMILE

COc1cc(ccc1O)C(C)=O

InChI

1S/C9H10O3/c1-6(10)7-3-4-8(11)9(5-7)12-2/h3-5,11H,1-2H3
DFYRUELUNQRZTB-UHFFFAOYSA-N

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Categorie correlate

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

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Certificati d'analisi (COA)

Lot/Batch Number
SDBB1075
STBL0772
STBK6806
STBK5573
STBK1089

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Elham Khanicheh et al.
Arteriosclerosis, thrombosis, and vascular biology, 33(9), 2187-2192 (2013-08-03)
Antioxidative drugs continue to be developed for the treatment of atherosclerosis. Apocynin is an nicotinamide adenine dinucleotide phosphate oxidase inhibitor with anti-inflammatory properties. We used contrast-enhanced ultrasound molecular imaging to assess whether short-term apocynin therapy in atherosclerosis reduces vascular oxidative
Jingfei Zhang et al.
Neuron, 82(1), 195-207 (2014-03-19)
Complement receptor 3 (CR3) activation in microglia is involved in neuroinflammation-related brain disorders and pruning of neuronal synapses. Hypoxia, often observed together with neuroinflammation in brain trauma, stroke, and neurodegenerative diseases, is thought to exacerbate inflammatory responses and synergistically enhance brain
Julio Madrigal-Matute et al.
Journal of the American Heart Association, 3(4) (2014-08-07)
Galectin-3 (Gal-3) participates in different mechanisms involved in atherothrombosis, such as inflammation, proliferation, or macrophage chemotaxis. Thus, there have been committed intensive efforts to elucidate the function of Gal-3 in cardiovascular (CV) diseases. The role of Gal-3 as a circulating
Ji Chen et al.
Hypertension (Dallas, Tex. : 1979), 61(3), 681-689 (2012-12-26)
Angiotensin-converting enzyme 2 (ACE2) is a lately discovered enzyme catalyzing Angiotensin II into Angiotensin 1-7. Angiotensin II has been reported to impair endothelial progenitor cell (EPC) function and is detrimental to stroke. Here, we studied the role of ACE2 in
Aurélia Lelli et al.
Glia, 61(9), 1542-1555 (2013-07-10)
The phagocyte NADPH oxidase Nox2 generates superoxide ions implicated in the elimination of microorganisms and the redox control of inflammatory signaling. However, the role of Nox2 in phagocyte functions unrelated to immunity or pathologies is unknown. During development, oriented cell
Visualizza tutti i documenti correlati

Questions

1–5 of 5 Questions  

  1. I'm looking for apocynin. Is A10809 the right product?

    1 answer

    1. Yes, apocynin is a common synonym for 4´-hydroxy-3´-methoxyacetophenone.

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  2. Can I use Product A10809, Apocynin, in cell culture?

    1 answer

    1. We do not specifically test our A10809 product for use in cell culture. However, several papers cite use of this compound in cell culture, in the micromolar range.

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  3. Can I dissolve Product A10809, Apocynin, in water?

    1 answer

    1. According to the chemicals encyclopedia published by the Royal Society of Chemistry, this product is slightly soluble in cold water and freely soluble in hot water. One publication cites preparation of stock solutions of this compound in cell culture medium at 2.5 mg/mL. See Heigold and Bauer, J. Leukocyte Biol., 72, 554-562 (2002).

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  4. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  5. How can I store stock solutions of Product A10809, Apocynin?

    1 answer

    1. While we ourselves have not tested solution stability, one publication cites storage at -20°C of stock solutions of this compound in cell culture medium at 2.5 mg/mL (Heigold and Bauer, J. Leukocyte Biol., 72, 554-562 (2002).

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