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81801

Sigma-Aldrich

Propylphosphonic anhydride solution

technical, ~50% in DMF

Sinonimo/i:

1-Propanephosphonic anhydride solution, 2,4,6-Tripropyl-1,3,5,2,4,6-trioxatriphosphorinane-2,4,6-trioxide solution, PPACA, T3P®

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25 ML
CHF 98.50
100 ML
CHF 271.00

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25 ML
CHF 98.50
100 ML
CHF 271.00

About This Item

Formula empirica (notazione di Hill):
C9H21O6P3
Numero CAS:
Peso molecolare:
318.18
Beilstein:
5079255
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22

CHF 98.50


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Grado

technical

Stato

solution

Concentrazione

~50% in DMF

Densità

1.090  g/cm3

Stringa SMILE

CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1

InChI

1S/C9H21O6P3/c1-4-7-16(10)13-17(11,8-5-2)15-18(12,14-16)9-6-3/h4-9H2,1-3H3
PAQZWJGSJMLPMG-UHFFFAOYSA-N

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Descrizione generale

Propylphosphonic anhydride is a highly reactive cyclic anhydride that is commonly used as a coupling agent and water scavenger.[1]

Applicazioni

Coupling reagent for peptide synthesis[2][3]; Preparation of other amides[4]; Synthesis of esters (depsipeptides)[5]

Caratteristiche e vantaggi

Some of its unique features include:
  • Broad functional group tolerance
  • Low epimerization tendency
  • By-products are water-soluble
  • High yield and purity


Note legali

T3P is a registered trademark of Archimica GmbH

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Eye Dam. 1 - Met. Corr. 1 - Repr. 1B - Skin Corr. 1B - Skin Sens. 1

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

143.6 °F

Punto d’infiammabilità (°C)

62 °C

Dispositivi di protezione individuale

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Certificati d'analisi (COA)

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I clienti hanno visto anche

H. Kessler et al.
Liebigs Ann. Chem., 1-1 (1986)
M. Feigel
Journal of the American Chemical Society, 108, 181-181 (1986)
H. Wissmann et al.
Angewandte Chemie (International Edition in English), 92, 129-129 (1980)
Propylphosphonic anhydride (T3P?): an efficient reagent for the one-pot synthesis of 1, 2, 4-oxadiazoles, 1, 3, 4-oxadiazoles, and 1, 3, 4-thiadiazoles.
Augustine JK, et al.
Tetrahedron, 65(48), 9989-9996 (2009)
H. Wissmann
Phosph. Sulfur Relat. Elem., 30, 645-645 (1986)

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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