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Sigma-Aldrich

Fmoc-Arg(Pbf)-OH

≥98.0% (HPLC)

Sinonimo/i:

Nα-Fmoc-Nω-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine, Nα-Fmoc-Nω-Pbf-L-arginine

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5 G
CHF 90.20
25 G
CHF 173.00
100 G
CHF 661.00
1 KG
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CHF 90.20


Spedizione prevista il29 marzo 2025


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Cambia visualizzazione
5 G
CHF 90.20
25 G
CHF 173.00
100 G
CHF 661.00
1 KG
Chiedi

About This Item

Formula empirica (notazione di Hill):
C34H40N4O7S
Numero CAS:
Peso molecolare:
648.77
Beilstein:
8302671
Numero MDL:
Codice UNSPSC:
12352209
eCl@ss:
32160406
ID PubChem:
NACRES:
NA.26

CHF 90.20


Spedizione prevista il29 marzo 2025


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Livello qualitativo

Saggio

≥98.0% (HPLC)

Stato

powder or crystals

Attività ottica

[α]/D -5.5±1.0°, c = 1 in DMF

Impiego in reazioni chimiche

reaction type: Fmoc solid-phase peptide synthesis

applicazioni

peptide synthesis

Gruppo funzionale

Fmoc

Temperatura di conservazione

−20°C

Stringa SMILE

Cc1c(C)c(c(C)c2CC(C)(C)Oc12)S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)OCC3c4ccccc4-c5ccccc35)C(O)=O

InChI

1S/C34H40N4O7S/c1-19-20(2)30(21(3)26-17-34(4,5)45-29(19)26)46(42,43)38-32(35)36-16-10-15-28(31(39)40)37-33(41)44-18-27-24-13-8-6-11-22(24)23-12-7-9-14-25(23)27/h6-9,11-14,27-28H,10,15-18H2,1-5H3,(H,37,41)(H,39,40)(H3,35,36,38)/t28-/m0/s1
HNICLNKVURBTKV-NDEPHWFRSA-N

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Descrizione generale

Fmoc-Arg(Pbf)-OH is used as a building block in peptide synthesis, providing protection to specific functional groups while allowing for efficient peptide bond formation.[1]

Applicazioni

Fmoc-Arg(Pbf)-OH is a Fmoc-protected amino acid derivative that can be used to create arginine-containing peptides.[2][3][4][5][6] The 2,2,4,6,7-pentamethyIdlhydrobenzofuran-5-sulfonyl group (Pbf) can be easily cleaved by trifluoroacetic acid (TFA).[7]

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


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Synthesis of positional-scanning libraries of fluorogenic peptide substrates to define the extended substrate specificity of plasmin and thrombin.
Backes B J, et al.
Nature Biotechnology, 18(2), 187-187 (2000)
A cobaltocenium?peptide bioconjugate shows enhanced cellular uptake and directed nuclear delivery.
Noor F, et al.
Angewandte Chemie (International Edition in English), 44(16), 2429-2432 (2005)
Side-Chain Unprotected Fmoc-Arg/His/Tyr-OH Couplings and Their Application in Solid-Phase Peptide Synthesis through a Minimal-Protection/Green Chemistry Strategy
Yang Y, et al.
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The 2, 2, 4, 6, 7-pentamethyldihydrobenzofuran-5-sulfonyl group (Pbf) as arginine side chain protectant.
Carpino L A, et al.
Tetrahedron Letters, 34(49), 7829-7832 (1993)

Questions

1–2 of 2 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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