Journal of medicinal chemistry, 38(15), 2860-2865 (1995-07-21)
Several 6-benzyl analogs of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (1; HEPT) were synthesized and evaluated for their anti-HIV-1 activity. LDA (lithium diisopropylamide) lithiation of 5-ethyluracil derivatives 7 and 8 and subsequent reaction with an aryl aldehyde gave 6-(arylhydroxymethyl)-5-ethyluracil derivatives 9-12. 6-(Arylhydroxymethyl)-5-isopropyluracil derivatives 15-18 were
Design and synthesis of novel chiral pyrrolidine-based diamines with C2-symmetry.
Nakajima M, et al.
Tetrahedron, 49(43), 9735-9750 (1993)
A new substrate for the Biginelli cyclocondensation: direct preparation of 5-unsubstituted 3,4-dihydropyrimidin-2(1H)-ones from a beta-keto carboxylic acid
Bussolari et al.
The Journal of organic chemistry, 65(20), 6777-6779 (2000-10-29)
The main contributors to the cooked off-flavor in heat-sterilized lychee juice (HLJ) were studied by means of molecular sensory science. The HLJ which elicited cooked cabbage/potato and onion/garlic off-flavor was compared with fresh lychee juice (FLJ) having desired sensory attributes
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