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128376

Sigma-Aldrich

4-Fluorobenzaldehyde

98%

Sinonimo/i:

p-Fluorobenzaldehyde

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About This Item

Formula condensata:
FC6H4CHO
Numero CAS:
459-57-4
Peso molecolare:
124.11
Beilstein:
385857
Numero CE:
207-293-6
Numero MDL:
MFCD00003378
Codice UNSPSC:
12352100
ID PubChem:
24847852
NACRES:
NA.22
Prezzi e disponibilità al momento non sono disponibili

Livello qualitativo

100

Saggio

98%

Stato

liquid

Indice di rifrazione

n20/D 1.521 (lit.)

P. ebollizione

181 °C/758 mmHg (lit.)

Punto di fusione

−10 °C (lit.)

Densità

1.157 g/mL at 25 °C (lit.)

Gruppo funzionale

aldehyde
fluoro

Stringa SMILE

[H]C(=O)c1ccc(F)cc1

InChI

1S/C7H5FO/c8-7-3-1-6(5-9)2-4-7/h1-5H
UOQXIWFBQSVDPP-UHFFFAOYSA-N

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Descrizione generale

4-Fluorobenzaldehyde, also known as p-Fluorobenzaldehyde is an organic compound often used in the condensation reactions for the synthesis of phenolic monomers. [1]

Applicazioni

4-Fluorobenzaldehyde was used in the preparation of pyrazolopyridine UR-13756[2].

Avvertenze

Warning

Indicazioni di pericolo

H226,H302,H319,H411

Classi di pericolo

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Flam. Liq. 3

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

132.8 °F - closed cup

Punto d’infiammabilità (°C)

56 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Certificati d'analisi (COA)

Lot/Batch Number
MKCW2569
MKCT4363
MKCS9862
0000263986
MKCT6107

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Mark C Bagley et al.
Future medicinal chemistry, 2(2), 193-201 (2011-03-24)
UR-13756 is a potent and selective p38 mitogen-activated protein kinase (MAPK) inhibitor, reported to have good bioavailability and pharmacokinetic properties and, thus, is of potential use in the treatment of accelerated aging in Werner syndrome. Irradiation of 2-chloroacrylonitrile and methylhydrazine
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Bis-aldehyde monomers 4-(4'-formyl-phenoxy)benzaldehyde (3a), 3-methoxy-4-(4'-formyl-phenoxy)benzaldehyde (3b), and 3-ethoxy-4-(4'-formyl-phenoxy)benzaldehyde (3c) were synthesized by etherification of 4-fluorobenzaldehyde (1) with 4-hydroxybenzaldehyde (2a), 3-methoxy-4-hydroxybenzaldehyde (2b), and 3-ethoxy-4-hydroxybenzaldehyde (2c), respectively. Each monomer was polymerized with p-phenylenediamine and 4,4'-diaminodiphenyl ether to yield six poly(azomethine)s. Single crystal
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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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