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481181

Sigma-Aldrich

Silver(I) sulfadiazine

98%

Sinonimo/i:

Silver sulfadiazine, Sulfadiazine silver

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About This Item

Formula empirica (notazione di Hill):
C10H9AgN4O2S
Numero CAS:
22199-08-2
Peso molecolare:
357.14
Numero CE:
244-834-5
Numero MDL:
MFCD00072101
Codice UNSPSC:
12352302
ID PubChem:
24871745
NACRES:
NA.23

Livello qualitativo

100

Saggio

98%

Stato

powder

Punto di fusione

285 °C (dec.) (lit.)

Stringa SMILE

Nc1ccc(cc1)S(=O)(=O)N([Ag])c2ncccn2

InChI

1S/C10H9N4O2S.Ag/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;/h1-7H,11H2;/q-1;+1
UEJSSZHHYBHCEL-UHFFFAOYSA-N

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Applicazioni

Silver(I) sulfadiazine (AgSD) is popularly used for treating second-degree burn wounds as it acts as an antimicrobial agent and prevents infections. Silver sulfadiazine-impregnated polyurethane (PU) foam, chitosan/chondroitin sulfate films may be used for wound dressing.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

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Certificati d'analisi (COA)

Lot/Batch Number
WXBF5144V
WXBF3160V
WXBD9153V
MKCS0591
MKCN0160

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Supelco

PHR1034

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Collagen human Bornstein and Traub Type I, acid soluble, powder, ~95% (SDS-PAGE)

Sigma-Aldrich

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Vincenzina Monzillo et al.
The new microbiologica, 35(2), 175-182 (2012-06-19)
The aim of this study was to compare the in vitro activity and the impact on bacterial adhesion of two different catheters, one impregnated with chlorhexidine-silver sulfadiazine (C-SS) and the other not impregnated with antibacterial agents. The antimicrobial coating prevented
Steven L Percival et al.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 20(5), 647-657 (2012-09-19)
Both chronic and acute dermal wounds are susceptible to infection due to sterile loss of the innate barrier function of the skin and dermal appendages, facilitating the development of microbial communities, referred to as biofilms, within the wound environment. Microbial
Chia-Yu Chu et al.
PloS one, 7(6), e38360-e38360 (2012-06-14)
Silver nanoparticles supported on nanoscale silicate platelets (AgNP/NSP) possess interesting properties, including a large surface area and high biocide effectiveness. The nanohybrid of AgNP/NSP at a weight ratio 7/93 contains 5-nm Ag particles supported on the surface of platelets with
[Modern possibilities of the local treatment of children with burn wounds].
L I Budkevich et al.
Khirurgiia, (10)(10), 48-51 (2012-12-14)
Meenakshi Venkataraman et al.
AAPS PharmSciTech, 14(1), 254-264 (2013-01-01)
The objective of the present study was to formulate stable silver sulfadiazine (SSD) nanosuspensions and nanogels suitable for topical delivery with a view to increase bactericidal activity in burn therapy. SSD nanosuspensions were formulated using the microprecipitation-high-pressure homogenization technique. An
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