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242632

Sigma-Aldrich

2-Chloroethyl methyl sulfide

97%

Sinonimo/i:

2-(Methylthio)ethyl chloride, Hemisulfur mustard

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About This Item

Formula condensata:
ClCH2CH2SCH3
Numero CAS:
542-81-4
Peso molecolare:
110.61
Beilstein:
1731033
Numero CE:
208-828-6
Numero MDL:
MFCD00000978
Codice UNSPSC:
12352100
ID PubChem:
24854574
NACRES:
NA.22

Saggio

97%

Forma fisica

liquid

Indice di rifrazione

n20/D 1.496 (lit.)

P. eboll.

55-56 °C/30 mmHg (lit.)

Densità

1.11 g/mL at 25 °C (lit.)

Temperatura di conservazione

2-8°C

Stringa SMILE

CSCCCl

InChI

1S/C3H7ClS/c1-5-3-2-4/h2-3H2,1H3
MYFKLQFBFSHBPA-UHFFFAOYSA-N

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Categorie correlate

Applicazioni

2-Chloroethyl methyl sulfide is a monofunctional chemical analog of sulfur mustard and has been used to study the potential of 2,6-dithiopurine as an antagonist of sulfur mustard.

Avvertenze

Danger

Indicazioni di pericolo

H226,H302,H311 + H331,H314,H350

Classi di pericolo

Acute Tox. 4 Oral - Carc. 1A - Flam. Liq. 3 - Skin Corr. 1B

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

107.6 °F - closed cup

Punto d’infiammabilità (°C)

42 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Certificati d'analisi (COA)

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HEPES BioPerformance Certified, suitable for cell culture, ≥99.0%

Sigma-Aldrich

H3784

HEPES

2-iodopropano contains copper as stabilizer, 99%

Sigma-Aldrich

148938

2-iodopropano

J R King et al.
Toxicology and applied pharmacology, 104(1), 167-179 (1990-06-01)
Previous research has shown the isolated perfused porcine skin flap (IPPSF) to be a novel in vitro experimental model for investigating xenobiotic percutaneous absorption. In this study, the IPPSF was used to biochemically and morphologically assess the dermatotoxicity of 2-chloroethyl
Y W Sohn et al.
Carcinogenesis, 17(6), 1361-1364 (1996-06-01)
Vinthionine (S-vinyl-DL-homocysteine) is hepatocarcinogenic in rats and mice. [Vinyl-14C]vinthionine binds covalently to rat liver DNA, RNA and protein in vivo, but not in vitro. This amino acid is directly mutagenic in Salmonella typhimurium TA100 and TA1535; the mechanism of its
Bruna Scaggiante et al.
Hematological oncology, 31(2), 110-116 (2012-08-30)
The elongation factor 1A proteins (eEF1A1/A2) are known to play a role in tumours. We previously found that a more basic isoform of eEF1A (MBI-eEF1A) is present in the cytoskeletal/nuclear-enriched extracts of CCRF-CEM T-lymphoblasts but not in those of normal
G R Klinefelter et al.
Journal of andrology, 18(2), 139-150 (1997-03-01)
In a previous study, we found that ethane dimethanesulphonate (EDS) compromised the fertilizing ability of proximal cauda epididymal sperm from the rat within 4 days of exposure, an effect that persisted in castrated, testosterone (T)-implanted animals, establishing direct action on
K Leslie Powell et al.
Chemical research in toxicology, 23(3), 497-503 (2010-01-07)
Sulfur mustard (bis-(2-chloroethyl)sulfide) is a well-known chemical warfare agent that induces debilitating cutaneous toxicity in exposed individuals. It is also known to be carcinogenic and mutagenic because of its ability to damage DNA via electrophilic attack. We previously showed that

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