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153516

Sigma-Aldrich

Lactobionic acid

97% (TLC)

Sinonimo/i:

4-O-β-D-Galactopyranosyl-D-gluconic acid

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CHF 136.00
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CHF 389.00

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25 G
CHF 136.00
100 G
CHF 389.00

About This Item

Formula empirica (notazione di Hill):
C12H22O12
Numero CAS:
96-82-2
Peso molecolare:
358.30
Beilstein:
95054
Numero CE:
202-538-3
Numero MDL:
MFCD00078147
Codice UNSPSC:
12352201
ID PubChem:
329750828
NACRES:
NA.25

CHF 136.00

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Origine biologica

synthetic

Livello qualitativo

200

Saggio

97% (TLC)

Stato

powder or crystals

Attività ottica

[α]20/D +25°, c = 10 in H2O

Colore

white

Punto di fusione

113-118 °C (lit.)

Solubilità

5%, clear, colorless

Temperatura di conservazione

room temp

Stringa SMILE

OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)C(O)=O

InChI

1S/C12H22O12/c13-1-3(15)10(7(18)8(19)11(21)22)24-12-9(20)6(17)5(16)4(2-14)23-12/h3-10,12-20H,1-2H2,(H,21,22)/t3-,4-,5+,6+,7-,8-,9-,10-,12+/m1/s1
JYTUSYBCFIZPBE-AMTLMPIISA-N

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Applicazioni

Lactobionic acid, an α-hydroxyacid (AHA) with antioxidation activity, is used in the development of cosmeceuticals for skin. Lactobionic acid is used in the development of targeting drug delivery systems, such as microcapsules.

Altre note

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
BCCH2355
BCCH9186
BCCG8405
BCCF8013
BCCF4590

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Cys-Gly ≥85% (TLC)

Sigma-Aldrich

C0166

Cys-Gly

Calcium lactobionate monohydrate ≥98.0% (KT)

Sigma-Aldrich

21190

Calcium lactobionate monohydrate

Gluconolactone 99.0-101.0%, meets USP testing specifications

Sigma-Aldrich

G2164

Gluconolactone

Lactobionic acid European Pharmacopoeia (EP) Reference Standard

Y0000257

Lactobionic acid

Calcium lactobionate monohydrate 98.0-102.0% (EDTA titration)

Sigma-Aldrich

L3375

Calcium lactobionate monohydrate

Calcium lactobionate United States Pharmacopeia (USP) Reference Standard

USP

1086902

Calcium lactobionate

USP

USP

1356825

Lactobionic acid

Barbara A Green et al.
Clinics in dermatology, 27(5), 495-501 (2009-08-22)
The hydroxyacids are represented by the alpha-hydroxyacids, beta-hydroxyacids, polyhydroxy acids, and bionic acids. Together, these ingredients form a class of compounds with unparalleled benefits to the skin and unprecedented usage in the cosmeceutical market in cosmetic and therapeutic formulations alike.
C Charloux et al.
Free radical biology & medicine, 19(5), 699-704 (1995-11-01)
Superoxide and hydroxyl free radicals are strongly implicated in the deleterious effects of reperfusion of grafted organs. Iron ions are critical in the Fenton-like reaction that generates oxygen-free radicals from H2O2. Using the ADP/Fe2+/H2O2 .OH-generating system, we demonstrated that components
K M Kamruzzaman Selim et al.
Journal of materials science. Materials in medicine, 20(9), 1945-1953 (2009-04-15)
In the current study, beta-galactose-carrying lactobionic acid (LA) was conjugated on the surface of mercaptoacetic acid-coated cadmium sulfide nanoparticles (CSNPs) to ensure specific recognition of liver cells (hepatocytes) and to enhance biocompatibility. Maltotrionic acid-coated CSNPs (MCSNPs) were also prepared for
Maryam Enteshari et al.
Foods (Basel, Switzerland), 9(6) (2020-06-18)
The simultaneous production of lactulose (LAU), lactobionic acid (LBA), and organic acids from sweet and acid whey permeate (SWP and AWP) via catalytic synthesis (5% Ru/C) was studied in a continuous stirred-tank reactor. At selected conditions (60 °C, 60 bar
Kimberley A Stannard et al.
Cancer letters, 299(2), 95-110 (2010-09-10)
High level galectin-1 expression results in cancer cell evasion of the immune response, increased tumour survival and aggressive metastases. Using a galectin-1 polyclonal antibody, high levels of galectin-1 protein were shown to be expressed by breast cancer cells established from
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Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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