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Merck
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Documenti

128635

Sigma-Aldrich

2-Hydroxyethyl methacrylate

contains ≤250 ppm monomethyl ether hydroquinone as inhibitor, 97%

Sinonimo/i:

1,2-Ethanediol mono(2-methylpropenoate), Glycol methacrylate, HEMA

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About This Item

Formula condensata:
CH2=C(CH3)COOCH2CH2OH
Numero CAS:
868-77-9
Peso molecolare:
130.14
Beilstein:
1071583
Numero CE:
212-782-2
Numero MDL:
MFCD00002863
Codice UNSPSC:
12162002
ID PubChem:
24847870
NACRES:
NA.23

Densità del vapore

5 (vs air)

Tensione di vapore

0.01 mmHg ( 25 °C)

Saggio

97%

Forma fisica

liquid

contiene

≤250 ppm monomethyl ether hydroquinone as inhibitor

Indice di rifrazione

n20/D 1.453 (lit.)

P. eboll.

67 °C/3.5 mmHg (lit.)

Densità

1.073 g/mL at 25 °C (lit.)

Temperatura di conservazione

2-8°C

Stringa SMILE

CC(=C)C(=O)OCCO

InChI

1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3
WOBHKFSMXKNTIM-UHFFFAOYSA-N

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Categorie correlate

Descrizione generale

2-Hydroxyethyl methacrylate (HEMA) was the first monomer to be used to synthesize hydrogels for biomedical applications.The water swelling properties of HEMA are enhanced by copolymerization with more hydrophilic monomers.HEMA finds wide applications for drug delivery.

Applicazioni

HEMA is used in the synthesis of biologically functional poly (2-hydroxyethyl methacrylate) (PHEMA) coplymers. It is also used to prepare light responsive membranes of PHEMA, HEMA/ acrylamide based specific drug release hydrogel, and water soluble HEMA/methacrylic acid hydrogel for drug delivery. Effects of HEMA on the migration of dental pulp stem cells (in vitro) may be studied.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H317,H319

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

222.8 °F - closed cup

Punto d’infiammabilità (°C)

106 °C - closed cup

Certificati d'analisi (COA)

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Giovanna C R M Schver et al.
International journal of pharmaceutics, 581, 119292-119292 (2020-04-04)
The use of water-insoluble carriers for amorphous solid dispersions (ASDs) has attracted more recent interest as the kinetic solubility profiles (KSP) from these systems can achieve a more sustained level of supersaturation when compared with ASDs based on water-soluble polymers.
Drake W Williams et al.
Journal of endodontics, 39(9), 1156-1160 (2013-08-21)
Cell migration is an important step in pulpal wound healing. Although components in the resin-based dental materials are known to have adverse effects on pulp wound healing including proliferation and mineralization, their effects on cell migration have been scarcely examined.
Influence of the ionic character of a drug on its release rate from hydrogels based on 2-hydroxyethylmethacrylate and acrylamide synthesized by photopolymerization
Gomez ML, et al.
Express Polymer Letters, 6(30, 189-197 (2012)
Thomas J Dursch et al.
Biomaterials, 35(2), 620-629 (2013-10-24)
Two-photon confocal microscopy and back extraction with UV/Vis-absorption spectrophotometry quantify equilibrium partition coefficients, k, for six prototypical drugs in five soft-contact-lens-material hydrogels over a range of water contents from 40 to 92%. Partition coefficients were obtained for acetazolamide, caffeine, hydrocortisone
Preparation of Light-responsive Membranes by a Combined Surface Grafting and Postmodification Process.
Scholler K, et al.
Journal of Visualized Experiments, 85, e51680-e51680 (2014)
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