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Merck

TRPV1

transient receptor potential cation channel, subfamily V, member 1

Sinonimi:
VR1
Specie:
ID UniProtKB:
ID gene:
  • Human(7442) Summary: Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(193034) transient receptor potential cation channel, subfamily V, member 1
  • Rat(83810) transient receptor potential cation channel, subfamily V, member 1
  • domestic cat(101093406) transient receptor potential cation channel, subfamily V, member 1
  • chicken(395259) transient receptor potential cation channel, subfamily V, member 1
  • naked mole-rat(101720480) transient receptor potential cation channel, subfamily V, member 1
  • Domestic Rabbit(100008926) transient receptor potential cation channel, subfamily V, member 1
  • domestic cat(100303454) transient receptor potential cation channel, subfamily V, member 1
  • Zebrafish(561195) transient receptor potential cation channel, subfamily V, member 1
  • cow(539074) transient receptor potential cation channel, subfamily V, member 1
  • domestic guinea pig(100135466) transient receptor potential cation channel, subfamily V, member 1
  • Horse(100034158) transient receptor potential cation channel, subfamily V, member 1
  • sheep(101110158) transient receptor potential cation channel, subfamily V, member 1
  • dog(445457) transient receptor potential cation channel, subfamily V, member 1

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Small Molecule - Agonist

N° Catalogo
Descrizione
Specie
Dihydrocapsaicin, from Capsicum sp., ≥85%,
Specie
rat, human
N-Vanillylnonanamide, ≥97%, powder,
Specie
rat
N-Oleoylethanolamine, ~98% (TLC),
Specie
human, mouse, rat

Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
SB-366791, ≥98% (HPLC), powder,
Specie
human
6-Iodonordihydrocapsaicin, ≥98% (HPLC), solid,
Specie
human
Capsazepine, ≥98% (HPLC), solid,
Specie
human, rat
Capsaicin, ≥95%, from Capsicum sp.,
Specie
rat, human
Capsaicin, natural,
Specie
rat, human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anticorpo anti-recettore della capsaicina, CT, serum, Chemicon®,
Reattività con
rat
Applicazione
immunohistochemistry
Anti-TRPV1 antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
western blot
Anti-TRPV1 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
ELISA
western blot
Monoclonal Anti-TRPV1 antibody produced in mouse, clone 1F5, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot
Anti-TRPV1 Antibody, clone 1N19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human, monkey, mouse
Applicazione
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
Olvanil, powder,
Specie
human
Capsaicin, ≥95%, from Capsicum sp.,
Specie
rat, human
Acetaminofene, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Capsaicin, natural,
Specie
rat, human
Acetaminofene, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human

Small Molecule - Mixed Agonist/Antagonist

N° Catalogo
Descrizione
Specie
N-Vanillylnonanamide, ≥97%, powder,
Specie
rat
Capsazepine, ≥98% (HPLC), solid,
Specie
human, rat

Small Molecule - Opener

N° Catalogo
Descrizione
Specie
Capsaicin, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Capsaicin, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human
Capsaicin, analytical standard,
Specie
human
Capsaicin, phyproof® Reference Substance,
Specie
human
Capsaicin, European Pharmacopoeia (EP) Reference Standard,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human TRPV1,
Specie
human
MISSION® esiRNA, targeting mouse Trpv1,
Specie
mouse