Passa al contenuto
Merck

HTR2A

5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled

Sinonimi:
5-HT2A, HTR2
Specie:
ID UniProtKB:
ID gene:
  • Human(3356) Summary: This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  • Mouse(15558) 5-hydroxytryptamine (serotonin) receptor 2A
  • Rat(29595) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • dog(403882) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • naked mole-rat(101708395) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • Horse(100009685) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • chicken(428070) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • domestic guinea pig(100135545) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • domestic cat(101081108) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • cow(407230) 5-hydroxytryptamine (serotonin) receptor 2A

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

N° Catalogo
Descrizione
Specie
(±)-DOI hydrochloride, ≥98% (HPLC), solid,
Specie
human
Aripiprazole solution, 1.0 mg/mL (50:50 Methanol/Water with 1% 1N HCl), ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
α-Methylserotonin maleate salt, ≥98% (HPLC),
Specie
human
Nortriptyline hydrochloride, ≥98% (HPLC), powder,
Specie
human
Mianserin hydrochloride, ,
Specie
human

Small Molecule - Allosteric Modulator

N° Catalogo
Descrizione
Specie
DCEBIO, ≥98% (HPLC), solid,
Specie
human

Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
M100907, ≥98% (HPLC),
Specie
human
Haloperidol solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
2,2-Diphenylethylamine, 96%,
Specie
rat
Haloperidol, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Haloperidol, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anticorpo anti-recettore per la serotonina 2A/HTR2A, clone 9B11.1, clone 9B11.1, from mouse,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
Anti-HTR2A, affinity isolated antibody,
Reattività con
human, rat
Applicazione
immunohistochemistry
western blot
Anti-HTR2A antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
western blot
Anti-5-HT-2A antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
ELISA
immunofluorescence

immunohistochemistry
Anti-Serotonin 2A (5-HT2A) Receptor (22-41) Rabbit pAb, liquid, Calbiochem®,
Reattività con
mouse, rat, sheep
Applicazione

Small Molecule - Blocker

N° Catalogo
Descrizione
Specie
Mianserin hydrochloride, ,
Specie
human
Trazodone hydrochloride, ≥99% (HPLC), powder,
Specie
human
Pimozide, ,
Specie
human, mouse, rat
Trimipramine maleate salt, ≥98% (TLC), powder,
Specie
human
Zimelidine dihydrochloride, solid,
Specie
human

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
Phenethylamine, 99%,
Specie
rat, mouse, human
Phenethylamine, ≥99%,
Specie
rat, mouse, human
Trazodone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
Phenethylamine, purified by redistillation, ≥99.5%,
Specie
rat, mouse, human
Trazodone hydrochloride impurity standard, British Pharmacopoeia (BP) Reference Standard,
Specie
human

Small Molecule - Ligand

N° Catalogo
Descrizione
Specie
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Specie
human

Small Molecule - Metabolite

N° Catalogo
Descrizione
Specie
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Specie
human

Small Molecule - Mixed Agonist/Antagonist

N° Catalogo
Descrizione
Specie
Mifepristone, ≥98%,
Specie
human, mouse, rat
Haloperidol, powder,
Specie
human, rat
Clozapine, ,
Specie
human, rat

Small Molecule - Precursor

N° Catalogo
Descrizione
Specie
5-Hydroxy-L-tryptophan, powder,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Htr2a,
Specie
mouse