Passa al contenuto
Merck

DRD4

dopamine receptor D4

Sinonimi:
D4DR
Specie:
ID UniProtKB:
ID gene:
  • Human(1815) Summary: This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008]
  • Mouse(13491) dopamine receptor D4
  • Rat(25432) dopamine receptor D4
  • naked mole-rat(101708437) dopamine receptor D4
  • dog(448805) dopamine receptor D4
  • domestic guinea pig(100733356) dopamine receptor D4
  • dog(607223) dopamine receptor D4
  • chicken(423016) dopamine receptor D4

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

N° Catalogo
Descrizione
Specie
PD 168,077 maleate salt, powder,
Specie
human
Apomorphine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Ropinirole hydrochloride, powder, ≥98% (HPLC),
Specie
human
Pramipexole dihydrochloride, >98% (HPLC), powder,
Specie
human
Ropinirole Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human

Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
L-745,870 hydrochloride, ,
Specie
human
U-101958 maleate salt, solid,
Specie
human
L-741,626, ≥98% (HPLC),
Specie
human
Chlorpromazine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
Chlorpromazine hydrochloride, meets USP testing specifications,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-Drd4 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
Anti-DRD4 Antibody, clone 2B9, clone 2B9, from mouse,
Reattività con
human, mouse, rat
Applicazione
immunocytochemistry
western blot
Anti-Dopamine D4 Receptor Antibody, extracellular domain, Chemicon®, from rabbit,
Reattività con
mouse
Applicazione
ELISA
western blot
Anti-Dopamine D₄ Receptor Rabbit pAb, lyophilized, Calbiochem®,
Reattività con
human, rat
Applicazione

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
GBR 12909 dihydrochloride, solid, ≥98% (HPLC),
Specie
human
Amoxapine, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Amoxapine, 1.0 mg/mL in methanol, certified reference material, Cerilliant®,
Specie
human
Amoxapine, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human
Amoxapine, ,
Specie
human

Small Molecule - Metabolite

N° Catalogo
Descrizione
Specie
3-Hydroxy-4-methoxyphenethylamine hydrochloride, ,
Specie
human
3-Methoxytyramine hydrochloride, ≥95.5%, crystalline,
Specie
human

Small Molecule - Mixed Agonist/Antagonist

N° Catalogo
Descrizione
Specie
BP897, >98% (HPLC), solid,
Specie
human, rat
Haloperidol, powder,
Specie
human, rat
Clozapine, ,
Specie
human, rat

Small Molecule - Precursor

N° Catalogo
Descrizione
Specie
3,4-Dihydroxy-L-phenylalanine, ≥98% (TLC),
Specie
mouse, human, rat
3,4-Dihydroxy-DL-phenylalanine, ,
Specie
mouse, human, rat

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Drd4,
Specie
mouse