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Principaux documents

S1885

Sigma-Aldrich

Suberic acid bis(N-hydroxysuccinimide ester)

≥95%, powder

Synonyme(s) :

Disuccinimidyl suberate, Disuccinimidyl octanedioate, Disuccinimidyl suberate (DSS)

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500 MG
106.00 CHF
1 G
120.00 CHF
5 G
354.00 CHF

106.00 CHF


Date d'expédition estimée le29 mai 2025


Devis pour commande en gros

Sélectionner une taille de conditionnement

Changer de vue
500 MG
106.00 CHF
1 G
120.00 CHF
5 G
354.00 CHF

About This Item

Formule empirique (notation de Hill) :
C16H20N2O8
Numéro CAS:
Poids moléculaire :
368.34
Numéro MDL:
Code UNSPSC :
12352100
ID de substance PubChem :
Nomenclature NACRES :
NA.21

106.00 CHF


Date d'expédition estimée le29 mai 2025


Devis pour commande en gros

Essai

≥95%

Forme

powder

Pertinence de la réaction

reagent type: cross-linking reagent

Solubilité

chloroform: 50 mg/mL
DMF: soluble
aqueous buffer: slightly soluble (may require 5-10% organic solvent in coupling mixture.)

Groupe fonctionnel

imide

Température de stockage

2-8°C

Chaîne SMILES 

O=C(CCCCCCC(=O)ON1C(=O)CCC1=O)ON2C(=O)CCC2=O

InChI

1S/C16H20N2O8/c19-11-7-8-12(20)17(11)25-15(23)5-3-1-2-4-6-16(24)26-18-13(21)9-10-14(18)22/h1-10H2

Clé InChI

ZWIBGKZDAWNIFC-UHFFFAOYSA-N

Description générale

Suberic acid bis(N-hydroxysuccinimide ester) is a homobifunctional cross-linking reagent with amine reactivity. Typically coupled to molecules containing primary amine by amide bond buffered at pH 7.5 (6.5-8.5). Suberic acid bis(N-hydroxysuccinimide ester) incorporates an 8-atom linker.

Application

Suberic acid bis(N-hydroxysuccinimide ester) has been:
  • supplemented in pierce lysis buffer used for immunoprecipitation[1]
  • used to conjugate the oligonucleotide standards to gelatin[2]
  • used in cross-linking of ASC (apoptosis-associated speck-like protein containing a caspase recruitment domain) oligomers[3]

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Certificats d'analyse (COA)

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Aljaž Gaber et al.
Scientific reports, 8(1), 13269-13269 (2018-09-07)
Cell-surface tumor marker EpCAM plays a key role in proliferation, differentiation and adhesion processes in stem and epithelial cells. It is established as a cell-cell adhesion molecule, forming intercellular interactions through homophilic association. However, the mechanism by which such interactions
Bastien Casu et al.
Scientific reports, 7(1), 14907-14907 (2017-11-04)
The increasing frequency of antimicrobial resistance is a problem of global importance. Novel strategies are urgently needed to understand and inhibit antimicrobial resistance gene transmission that is mechanistically related to bacterial virulence functions. The conjugative transfer of plasmids by type
Scutellarin suppresses NLRP3 inflammasome activation in macrophages and protects mice against bacterial sepsis
Liu Y, et al.
Frontiers in Pharmacology, 8, 975-975 (2018)
Quantification and calibration of images in fluorescence microscopy
Baskin DS, et al.
Analytical Biochemistry, 404(2), 118-126 (2010)
Combined effects of FH (E404D) and ACOX2 (R409H) cause metabolic defects in primary cardiac malignant tumor
Zhou X, et al.
Cell death discovery, 5(1), 18-18 (2018)

Questions

1–2 of 2 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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