Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
D3525
Diosmin
analytical standard
Synonyme(s) :
3′,5,7-Trihydroxy-4′-methoxyflavone 7-rutinoside, Barosmin, Buchu resin, Diosmetin 7-O-rhamnosylglucoside, Diosmetin 7-rutinoside
Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
About This Item
Formule empirique (notation de Hill) :
C28H32O15
Numéro CAS:
Poids moléculaire :
608.54
Numéro CE :
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24
Le tarif et la disponibilité ne sont pas disponibles actuellement.
Produits recommandés
Qualité
analytical standard
Niveau de qualité
Technique(s)
HPLC: suitable
gas chromatography (GC): suitable
Application(s)
cleaning products
cosmetics
food and beverages
personal care
Format
neat
Température de stockage
2-8°C
Chaîne SMILES
COc1ccc(cc1O)C2=CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2
InChI
1S/C28H32O15/c1-10-21(32)23(34)25(36)27(40-10)39-9-19-22(33)24(35)26(37)28(43-19)41-12-6-14(30)20-15(31)8-17(42-18(20)7-12)11-3-4-16(38-2)13(29)5-11/h3-8,10,19,21-30,32-37H,9H2,1-2H3/t10-,19+,21-,22+,23+,24-,25+,26+,27+,28+/m0/s1
Clé InChI
GZSOSUNBTXMUFQ-YFAPSIMESA-N
Vous recherchez des produits similaires ? Visite Guide de comparaison des produits
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Actions biochimiques/physiologiques
Citrus flavonoid. Modification of hesperidin. Studied for its chemopreventive properties, including anti-proliferative and anti-inflammatory.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Gloves, type N95 (US)
Faites votre choix parmi les versions les plus récentes :
Déjà en possession de ce produit ?
Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Les clients ont également consulté
Thangarasu Silambarasan et al.
European journal of pharmacology, 679(1-3), 81-89 (2012-01-24)
The present study was aimed to evaluate the antihypertensive effect of diosmin in deoxycorticosterone acetate (DOCA)-salt induced hypertension in male Wistar rats. Hypertension was induced in uninephrectomized rats by weekly twice subcutaneous injection of DOCA (25 mg/kg body weight) and
M Alcaraz et al.
Dento maxillo facial radiology, 40(5), 310-314 (2011-06-24)
The aim of this study was to evaluate the antioxidant substances present in the human diet with an antimutagenic protective capacity against genotoxic damage induced by exposure to X-rays in an attempt to reduce biological damage to as low a
Tran Duc Dung et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(5), 1802-1810 (2012-02-01)
Hepatocellular carcinoma is a common type of cancer with poor prognosis. This study examines the in vitro and in vivo mechanisms of diosmin on human hepato-cellular carcinoma HA22T cell proliferation inhibition. HA22T cells were treated with different diosmin concentrations and
Guy Lewin et al.
Journal of natural products, 76(1), 8-12 (2012-12-20)
Enhancement of the water solubility by disruption of molecular planarity has recently been reviewed as a feasible approach in small-molecule drug discovery programs. We applied this strategy to some natural flavone glycosides, especially diosmin, a highly insoluble citroflavonoid prescribed as
Jacqueline M Cohen et al.
Chest, 141(2), 308-320 (2012-02-09)
Postthrombotic syndrome (PTS) is a frequent, chronic complication of DVT. The effectiveness and safety of available treatments are unknown. The objective of this study was to systematically review the literature to assess whether pharmacologic and compression therapies are effective and
-
What is the Department of Transportation shipping information for this product?
1 answer-
Helpful?
-
-
How should Product D3525, Diosmin, be dissolved?
1 answer-
Diosmin is soluble in DMSO at 10 mM, per following paper:Zhang, S., et al., "Flavonoids as Aryl Hydrocarbon Receptor Agonists/Antagonists: Effects of Structure and Cell Context." Environ. Health. Perspect., 111, 1877-1882 (2003).
Helpful?
-
-
Does Product D3525, diosmin absorb in the UV spectrum? If so, what is the ?max?
1 answer-
Yes. Diosmin has the following UV absorbance properties: λmax: 255 nm, 268 nm, 345 nm (ethanol) Extinction coefficient: EmM = 19.05, 17.78, and 19.95.Referenced from: chemicals encyclopedia published by the Royal Society of Chemistry, 10th ed., Entry# 3300.
Helpful?
-
-
Is Product D3525, Diosmin, synthetic or from a natural source?
1 answer-
Diosmin is typically isolated from a plant source (orange or lemon). This information can be found on Certificate of Origin (CofO lot-specific). The link to CofO is located on the Product Detail Page.
Helpful?
-
-
Product D3525, Diosmin, is a rutinoside derivative. Does Sigma-Aldrich list any other rutinosides?
1 answer-
Yes, we have two others: H5254, Hesperidin and 36428, Keracynin chloride.
Helpful?
-
Active Filters
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
Contacter notre Service technique
