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114189

Sigma-Aldrich

Acetyl chloride

reagent grade, 98%

Synonyme(s) :

Acetic acid chloride, Acetic chloride, Ethanoyl chloride

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25 G
39.70 CHF
500 G
69.00 CHF
1 KG
111.00 CHF

39.70 CHF


Date d'expédition estimée le26 mai 2025


Devis pour commande en gros

Sélectionner une taille de conditionnement

Changer de vue
25 G
39.70 CHF
500 G
69.00 CHF
1 KG
111.00 CHF

About This Item

Formule linéaire :
CH3COCl
Numéro CAS:
Poids moléculaire :
78.50
Beilstein:
605303
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352100
eCl@ss :
39050501
ID de substance PubChem :
Nomenclature NACRES :
NA.21

39.70 CHF


Date d'expédition estimée le26 mai 2025


Devis pour commande en gros

Qualité

reagent grade

Niveau de qualité

Densité de vapeur

2.7 (vs air)

Pression de vapeur

11.69 psi ( 20 °C)
32.33 psi ( 55 °C)

Essai

98%

Forme

liquid

Température d'inflammation spontanée

1353 °F

Limite d'explosivité

19 %

Indice de réfraction

n20/D 1.389 (lit.)

pb

52 °C (lit.)

Pf

−112 °C (lit.)

Densité

1.104 g/mL at 25 °C (lit.)

Groupe fonctionnel

acyl chloride

Chaîne SMILES 

CC(Cl)=O

InChI

1S/C2H3ClO/c1-2(3)4/h1H3

Clé InChI

WETWJCDKMRHUPV-UHFFFAOYSA-N

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Description générale

Acetyl chloride is used as an acylating reagent for electrophilic acetylation of alkynes, alkenes, arenes, saturated alkanes, enolates, and organometallics.[1]

Acetyl chloride is a colorless acyl halide. On reaction with ammonia and alcohols, it affords acetamide and esters of acetic acid, respectively.[2] Structural parameters and rotational constants of its isotopic forms have been evaluated from the microwave spectral investigations.[3]

Application

Acetyl chloride has been used in the Lepage and Roy fatty acids analysis, and robotic fatty acid analysis.[4] It may be used for the qualitative in situ synthesis of hydrogen chloride.[5]

Pictogrammes

FlameCorrosion

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B

Risques supp

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

41.0 °F - closed cup

Point d'éclair (°C)

5 °C - closed cup


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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Acetyl Chloride-Methanol as a Convenient Reagent for: A) Quantitative Formation of Amine Hydrochlorides B) Carboxylate Ester Formation C) Mild Removal of Nt-Boc-Protective Group.
Nudelman A, et al.
Synthetic Communications, 28(3), 471-474 (1998)
Acetyl Chloride
Pearlman BA
eEROS (Encyclopedia of Reagents for Organic Synthesis) (2001)
Yu Hong Lin et al.
Lipids, 47(5), 527-539 (2012-03-21)
Large population studies show that polyunsaturated fatty acids are important for human health, but determining relationships between the health benefits and the fatty acid content has been hampered by the unavailability of labor-effective high-throughput technologies. An automated high throughput fatty
Microwave spectrum of acetyl chloride.
Sinnott, KM.
J. Chem. Phys. , 34(3), 851-861 (1961)
Eagleson M.
Concise Encyclopedia Chemistry, 4-4 (1994)

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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