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Merck

PS610

Paraoxon

analytical standard

Synonym(e):

O,O-Diethyl O-(4-nitrophenyl)-phosphat, Diethyl-p-nitrophenylphosphat, Paraoxon, Paraoxon-ethyl

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About This Item

Lineare Formel:
O2NC6H4OP(O)(OC2H5)2
CAS-Nummer:
Molekulargewicht:
275.20
Beilstein:
1915526
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:

Qualität

analytical standard

Verpackung

ampule of 100 mg

Hersteller/Markenname

Chem Service, Inc. PS-610

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Brechungsindex

n20/D 1.51 (lit.)

Dichte

1.274 g/mL at 25 °C (lit.)

Anwendung(en)

cleaning products
cosmetics
food and beverages
personal care

Format

neat

SMILES String

CCOP(=O)(OCC)Oc1ccc(cc1)[N+]([O-])=O

InChI

1S/C10H14NO6P/c1-3-15-18(14,16-4-2)17-10-7-5-9(6-8-10)11(12)13/h5-8H,3-4H2,1-2H3

InChIKey

WYMSBXTXOHUIGT-UHFFFAOYSA-N

Angaben zum Gen

human ... PON1(5444)

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Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem./physiol. Wirkung

Potenter irreversibler Acetylcholinesterase-Inhibitor

Piktogramme

Skull and crossbonesEnvironment

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 1 Dermal - Acute Tox. 1 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Lagerklassenschlüssel

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Analysenzertifikate (COA)

Lot/Batch Number

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. Is Product PS610, Paraoxon - analytical standard, a solid or a liquid?

    This is an oil or liquid at room temperature.

  5. What is Product PS610, Paraoxon - analytical standard, soluble in?

    This is freely soluble in diethyl ether, and in most other organic solvents.

  6. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  7. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Zoran Radić et al.
The Biochemical journal, 450(1), 231-242 (2012-12-12)
In the present paper we show a comprehensive in vitro, ex vivo and in vivo study on hydrolytic detoxification of nerve agent and pesticide OPs (organophosphates) catalysed by purified hBChE (human butyrylcholinesterase) in combination with novel non-pyridinium oxime reactivators. We
J Allen Crow et al.
Biochemical pharmacology, 84(9), 1215-1222 (2012-09-05)
Carboxylesterase type 1 (CES1) and CES2 are serine hydrolases located in the liver and small intestine. CES1 and CES2 actively participate in the metabolism of several pharmaceuticals. Recently, carbamate compounds were developed to inhibit members of the serine hydrolase family
D E Lorke et al.
Journal of applied toxicology : JAT, 29(6), 459-469 (2009-07-16)
K-oximes have recently been developed in the search for efficacious broad-band reactivators of acetylcholinesterase (AChE) inhibited by organophosphorus compounds (OPC). Before clinical use, their toxicity and efficacy need to be assessed, and there is clear demand for simple in vitro
Tamara C Otto et al.
Chemico-biological interactions, 203(1), 186-190 (2012-10-09)
In an effort to discover novel catalytic bioscavengers of organophosphorus (OP) nerve agents, cell lysates from a diverse set of bacterial strains were screened for their capacity to hydrolyze the OP nerve agents VX, VR, and soman (GD). The library
Guanglei Fu et al.
Talanta, 103, 110-115 (2012-12-04)
Highly sensitive colorimetric detection of organophosphate pesticides (OPs) was developed using Cu (I)-catalyzed click chemistry as the colorimetric signal amplification process between the acetylcholine esterase-acetylthiocholine system (AChE-ATCl) and azide- terminal alkyne-functionalized Au NPs as the colorimetric probe. It was demonstrated

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