569232-U

Discovery^® C18 (5 µm) HPLC Columns

L × I.D. 12.5 cm × 4.6 mm, HPLC Column

• Synonym(e): Discovery RP18 HPLC Column
• UNSPSC-Code: 41115700
• eCl@ss: 32110501
• NACRES: SB.52

Eigenschaften

• product name: Discovery^® C18 HPLC-Säule, 5 μm particle size, L × I.D. 12.5 cm × 4.6 mm
• Materialien: stainless steel column
• Agentur: suitable for USP L1
• Produktlinie: Discovery^®
• Leistungsmerkmale: endcapped
• Hersteller/Markenname: Discovery^®
• Verpackung: 1 ea of
• Kennzeichnungsgrad: 12% Carbon loading
• Parameter: ≤70 °C temp. range; 400 bar pressure (5801 psi)
• Methode(n): HPLC: suitable; LC/MS: suitable
• L × ID: 12.5 cm × 4.6 mm
• Oberflächenbereich: 300 m²/g
• Oberflächendeckung: 3 μmol/m²
• Verunreinigungen: <10 ppm metals
• Matrix: silica gel, high purity, spherical particle platform; fully porous particle
• Aktive Matrixgruppe: C18 (octadecyl) phase
• Partikelgröße: 5 μm
• Porengröße: 180 Å
• operating pH range: 2-8
• Anwendung(en): food and beverages
• Trenntechnik: reversed phase

Beschreibung

Allgemeine Beschreibung

Verwenden Sie Discovery® C18 für jede Methode, die eine C18-Säule erfordert. Durch die ausgezeichnete Peakform, Reproduzierbarkeit und Stabilität ist sie die Säule der Wahl für alle routinemäßigen bis anspruchsvollen C18-Methoden.

Anwendung

• Rat Pharmacokinetics and In Vitro Metabolite Identification of KM-819, a Parkinson′s Disease Candidate, Using LC-MS/MS and LC-HRMS.: This study underscores the utility of theDiscovery^® C18 HPLC Column in pharmacokinetic profiling and metabolite identification of a novel therapeutic agent, demonstrating its critical role in the development of Parkinson′s disease treatments (Choi et al., 2024).


• Determination of 2,4-dimethylhydroxybenzene by chromatographic methods in forensic toxicological research of biological material.: Highlights the application of the Discovery^® C18 HPLC Column in forensic toxicology, enhancing the detection and quantification of toxic substances within biological samples, vital for legal and medical investigations (Chernova et al., 2024).


• High-throughput microfluidic chip with silica gel-C18 channels for cyclotide separation.: Illustrates the integration of the Discovery^® C18 HPLC Column in a microfluidic setting for efficient and high-throughput separation of cyclotides, offering advancements in peptide and protein analysis (Ebrahimi et al., 2023).


• Priestia megaterium Metabolism: Isolation, Identification of Naringenin Analogues and Genes Elevated Associated with Nanoparticle Intervention.: This research utilizes the Discovery^® C18 HPLC Column for the advanced study of microbial metabolism under nanoparticle intervention, pushing the boundaries of biotechnological and pharmaceutical research (Al-Theyab et al., 2023).


• A practical strategy enabling more reliable identification of ginsenosides from Panax quinquefolius flower by dimension-enhanced liquid chromatography/mass spectrometry and quantitative structure-retention relationship-based retention behavior prediction.: Demonstrates the versatility of the Discovery^® C18 HPLC Column in complex botanical analyses, particularly in enhancing the reliability of ginsenoside identification, crucial for the development of herbal medicinal products (Sun et al., 2023).

Leistungsmerkmale und Vorteile

• Ausgezeichnete Reproduzierbarkeit
• Hervorragende Peakform bei basischen und sauren Analyten
• Stabile, gering blutende LC/MS-Trennungen
• Trennung von Peptiden und kleinen Proteinen
• Geringere Hydrophobität als viele vergleichbare C18-Säulen für schnellere Analysen

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Rechtliche Hinweise

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany