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Merck

T3651

Sigma-Aldrich

Anti-Tropomyosin antibody produced in rabbit

whole antiserum

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About This Item

MDL-Nummer:
UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Konjugat

unconjugated

Antikörperform

whole antiserum

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Enthält

15 mM sodium azide

Speziesreaktivität

chicken

Methode(n)

indirect immunofluorescence: 1:40 using cultured chicken fibroblasts
western blot: suitable

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

chicken ... TPM1(396366)

Allgemeine Beschreibung

Tropomyosin is a rigid, rod shaped protein, closely associated with actin filaments. In non-muscle cells grown in culture, tropomyosin is distributed periodically along the length of the stress fibers.

Spezifität

The antibody specifically reacts with tropomyosin (typical banded pattern of stress fibers) in cultured cells and two tropomyosin bands of total chicken gizzard extract by immunoblotting.

Immunogen

smooth muscle tropomyosin from chicken gizzard.

Anwendung

Anti-Tropomyosin antibody produced in rabbit has been used in western immunoblotting and immunofluorescence.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Differentiation of CD45?/CD31+ lung side population cells into endothelial and smooth muscle cells in vitro
Xu Y, et al.
International Journal of Molecular Medicine, 43(3), 1128-1138 (2019)
Fang Wang et al.
Journal of biomedicine & biotechnology, 2011, 435271-435271 (2011-12-22)
Familial hypertrophic cardiomyopathy (FHC) is a disease of cardiac sarcomeres. To identify molecular mechanisms underlying FHC pathology, functional and structural differences in three FHC-related mutations in recombinant α-Tm (V95A, D175N, and E180G) were characterized using both conventional and modified in
K Miyado et al.
Biochemical and biophysical research communications, 225(2), 427-435 (1996-08-14)
Tropomyosin is an actin-associated cytoskeletal protein expressed in muscle and non-muscle cells. There are several tropomyosin isoforms, and their cellular expression is known to be associated with transformation events caused by retroviral infection and chemical mutagens. We found that expression
Jürg P F Nüesch et al.
Journal of virology, 80(10), 4729-4739 (2006-04-28)
During a productive infection, the prototype strain of the parvovirus minute virus of mice (MVMp) induces dramatic morphological alterations in permissive A9 fibroblasts, culminating in cell lysis at the end of infection. These cytopathic effects (CPE) result from rearrangements and
Jürg P F Nüesch et al.
Proceedings of the National Academy of Sciences of the United States of America, 104(30), 12482-12487 (2007-07-20)
Autonomous parvoviruses induce severe morphological and physiological alterations in permissive host cells, eventually leading to cell lysis and release of progeny virions. Viral cytopathic effects (CPE) result from specific rearrangements and destruction of cytoskeletal micro- and intermediate filaments. We recently

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