T3526

Anti-TUBA1B (alpha-tubulin ubiquitous) Antibody

rabbit polyclonal

• Synonym(e): Anti-K-ALPHA-1
• MDL-Nummer: MFCD00145921
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Produktbezeichnung: Anti-Tubulin antibody produced in rabbit, whole antiserum
• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: whole antiserum
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Enthält: 15 mM sodium azide
• Speziesreaktivität: chicken, mouse
• Methode(n): indirect immunofluorescence: 1:80 using cultured fibroblasts; western blot: 1:200 using chicken gizzard extract or mouse brain extract
• UniProt-Hinterlegungsnummer: P68363
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: mouse ... Tuba1b(22143) , Tubb2a(22151) , Tubb2b(73710) , Tubb2c(227613)

Beschreibung

Allgemeine Beschreibung

Microtubules are composed of tubulin and several additional proteins designated microtubule associated proteins (MAPs). Tubulin is a heterodimer which consists of an α-chain and a β-chain, both of which have a molecular weight of approximately 55,000. Microtubules form an elaborate cytoplasmic network during interphase and are reorganized into the mitotic spindle during cell division.

Tubulin is an extremely conserved and negatively charged protein. It is expressed in all eukaryotic cells, but mainly in brains.

Spezifität

The product stains tubulin in cultured chicken fibroblasts or 3T3 mouse fibroblasts. Additional bands may be stained in immunoblotting.

Immunogen

microtubule proteins from brains of 13 day old chicken embryos

Anwendung

Anti-Tubulin antibody produced in rabbit has been used in immunoblotting and indirect immunofluorescence.

Biochem./physiol. Wirkung

αβ-tubulin heterodimers helps in formation of microtubules. Tubulin dimers exhibits GTPase activity, assembly and disassembly properties. It facilitates the construction of the flagellar apparatus.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)