SML1140

ML138

≥98% (HPLC)

• Synonym(e): 2-[5-[[(3,4-Dichlorophenyl)methyl]thio]-4-(2-furanylmethyl)-4H-1,2,4-triazol-3-yl]-pyridine, CID 44601470, CID44601470, ML-138
• Empirische Formel (Hill-System): C₁₉H₁₄Cl₂N₄OS
• CAS-Nummer: 1355243-24-1
• Molekulargewicht: 417.31
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825675
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 10 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: ClC1=CC(CSC2=NN=C(C3=NC=CC=C3)N2CC4=CC=CO4)=CC=C1Cl
• InChI: 1S/C19H14Cl2N4OS/c20-15-7-6-13(10-16(15)21)12-27-19-24-23-18(17-5-1-2-8-22-17)25(19)11-14-4-3-9-26-14/h1-10H,11-12H2
• InChIKey: QDXGAJIGONMOCL-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

ML138 (CID 44601470) is a highly selective agonist at kappa opioid receptors (KOR) that potently activate G protein coupling but weakly interact with β arrestin2.

ML138 is a highly selective agonist at kappa opioid receptors (KOR).

Leistungsmerkmale und Vorteile

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable