SML0665

LY-456236

≥98% (HPLC)

• Synonym(e): (4-Methoxy-phenyl)-(6-methoxy-quinazolin-4-yl)-amine hydrochloride, 6-Methoxy-N-(4-methoxyphenyl)-4-quinazolinamine hydrochloride, LY456236, MPMQ
• Empirische Formel (Hill-System): C₁₆H₁₅N₃O₂ · HCl
• CAS-Nummer: 338736-46-2
• Molekulargewicht: 317.77
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear (warmed)
• Lagertemp.: 2-8°C
• InChI: 1S/C16H15N3O2.ClH/c1-20-12-5-3-11(4-6-12)19-16-14-9-13(21-2)7-8-15(14)17-10-18-16;/h3-10H,1-2H3,(H,17,18,19);1H
• InChIKey: AVKFOWUSTVWZQN-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

LY-456236 is a selective mGlu1 receptor antagonist with an IC₅₀ value of 143 nM for mGlu1 compared to > 10 μM for mGlu5 receptors.

Leistungsmerkmale und Vorteile

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Piktogramme: GHS05,GHS07
• Signalwort: Danger
• H-Sätze: H302,H315,H318,H335,H413
• P-Sätze: P273 - P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 + P310
• Gefahreneinstufungen: Acute Tox. 4 Oral - Aquatic Chronic 4 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable