SML0045

Salvianolic acid A hydrate

≥98% (HPLC)

• Synonym(e): Dan phenolic acid A hydrate
• Empirische Formel (Hill-System): C₂₆H₂₂O₁₀ · xH₂O
• CAS-Nummer: 96574-01-5
• Molekulargewicht: 494.45 (anhydrous basis)
• MDL-Nummer: MFCD20527310
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825115
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: yellow
• Löslichkeit: H₂O: ≥19 mg/mL
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• SMILES String: O.OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)\C=C\c2ccc(O)c(O)c2\C=C\c3ccc(O)c(O)c3
• InChI: 1S/C26H22O10.H2O/c27-18-7-2-14(11-21(18)30)1-6-17-16(4-9-20(29)25(17)33)5-10-24(32)36-23(26(34)35)13-15-3-8-19(28)22(31)12-15;/h1-12,23,27-31,33H,13H2,(H,34,35);1H2/b6-1+,10-5+;/t23-;/m1./s1
• InChIKey: XFUSRNNWIRPEDG-FYLUTCCGSA-N

Beschreibung

Anwendung

Salvianolic acid A hydrate may be used in cell signaling studies.
Salvianolic acid A hydrate has been used as rosmarinic acid derivative for the inhibition of DNA polymerase e in human cell lines.[1]

Biochem./physiol. Wirkung

Cell protective antioxidant

Salvianolic acid A acts as scavengers of reactive oxygen species, reduces the adherence of leukocytes to endothelial cells, inhibits matrix metalloproteinases and inflammation.[2] It has cardioprotective effects as it suppresses apoptosis, reduces lipid peroxidation in damaged cardiac tissue and decreases the leakage of lactic acid dehydrogenase.[2][3]

Salvianolic acid A is cell protective antioxidant originally isolated from Salvia. It has been found to attenuate PDGF-induced ROS formation in hepatic stellate cells and protected against isoproterenol-induced myocardial damage in rats.

Sicherheitshinweise

• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable