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Merck

SMB00110

Sigma-Aldrich

Plumieride

≥95% (LC/MS-ELSD)

Synonym(e):

Agoniadin

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About This Item

Empirische Formel (Hill-System):
C21H26O12
CAS-Nummer:
Molekulargewicht:
470.42
UNSPSC-Code:
12352205
PubChem Substanz-ID:
NACRES:
NA.25

Assay

≥95% (LC/MS-ELSD)

Form

solid

Anwendung(en)

metabolomics
vitamins, nutraceuticals, and natural products

Lagertemp.

−20°C

SMILES String

COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3[C@@H]1C=C[C@]34OC(=O)C(=C4)[C@H](C)O

InChI

1S/C21H26O12/c1-8(23)10-5-21(33-18(10)28)4-3-9-11(17(27)29-2)7-30-19(13(9)21)32-20-16(26)15(25)14(24)12(6-22)31-20/h3-5,7-9,12-16,19-20,22-26H,6H2,1-2H3/t8-,9+,12+,13+,14+,15-,16+,19-,20-,21+/m0/s1

InChIKey

AOPMSFXOYJXDNJ-IRFSQMTFSA-N

Allgemeine Beschreibung

Natural product derived from plant source.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

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Sebastião de O Rebouças et al.
Journal of ethnopharmacology, 147(2), 474-480 (2013-03-27)
Himatanthus articulatus (Apocynaceae) is a plant native to the Amazon, popularly used to treat external ulcers, tumors, inflammations, cancer, syphilis and malaria. To investigate the in vivo genotoxic and mutagenic potential of this plant, using the comet assay and the
Mahabeer P Dobhal et al.
The Journal of organic chemistry, 69(19), 6165-6172 (2004-09-11)
Plumieride was isolated as one of the major components from the biologically active methanolic extract of the bark of Plumeria bicolor (family Apocynaceae). For investigating the effect of substituents on cytotoxic activity it was modified into a series of compounds.
M S Abdel-Kader et al.
Journal of natural products, 60(12), 1294-1297 (1998-01-15)
Bioassay-guided fractionation of the EtOAc extract of both Allamanda cathartica and Himatanthus fallax (Apocynaceae) using the Sc-7 yeast strain resulted in the isolation of the weakly cytotoxic isoplumericin and plumericin. In addition, the new lignan 7(R)-methoxy-8-epi-matairesional and three known compounds
R S Gupta et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 11(2-3), 169-174 (2004-04-09)
Oral feeding of male rats with plumieride (15 mg/rat/day) for the period of 60 days did not cause any significant change in the body weight of treated rats. However, the weights of testes, epididymides, seminal vesicle and ventral prostate were
T N Tiwari et al.
Phytotherapy research : PTR, 16(4), 393-394 (2002-07-12)
Plumieride has been isolated as an active principle of the leaves of Allamanda cathartica. It showed strong fungitoxicity against some dermatophytes causing dermatomycosis to animals and human beings. It exhibited a noncytotoxic nature against a P(388) mouse leukaemia cell line.

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