This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21. [provided by RefSeq, Jul 2008]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 485-584 of human Cytokeratin 10 (P13645).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Anwendung
WB, IF/ICC
Lagerklassenschlüssel
10 - Combustible liquids
WGK
WGK 1
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