SAB5700327

Anti-Phospho-mTOR-S2448 antibody produced in rabbit

• Synonym(e): FRAP, FRAP1, FRAP2, MTOR, RAFT1, RAPT1, SKS, mTOR
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: 288
• Speziesreaktivität: human, mouse, rat
• Konzentration: 0.88 mg/ml
• Methode(n): immunofluorescence: 1:50-1:200; western blot: 1:500-1:2000
• UniProt-Hinterlegungsnummer: P42345
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pSer2448)
• Angaben zum Gen: human ... mTOR(2475)

Beschreibung

Allgemeine Beschreibung

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.

Immunogen

A synthetic phosphorylated peptide around S2448 of human mTOR (NP_004949.1).

Physikalische Form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Lagerung und Haltbarkeit

Store at -20℃. Avoid freeze / thaw cycles.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable