SAB4500455

Anti-CBP antibody produced in rabbit

affinity isolated antibody

• Synonym(e): CREB-binding protein, CREBBP
• MDL-Nummer: MFCD02262673
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 265 kDa
• Speziesreaktivität: human, rat, mouse
• Konzentration: ~1 mg/mL
• Methode(n): ELISA: 1:20000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI-Hinterlegungsnummer: Q92793
• UniProt-Hinterlegungsnummer: Q92793
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... CREBBP(1387)

Beschreibung

Allgemeine Beschreibung

Anti-CBP Antibody detects endogenous levels of total CBP protein. CREB binding protein (CBP) is a histone acetyltransferase, which is part of the KAT3 family of histone acetyltransferases. The gene encoding it is localized on human chromosome 16p13.3.

Immunogen

The antiserum was produced against synthesized peptide derived from human CBP.

Immunogen Range: 1501-1550

Biochem./physiol. Wirkung

CREB binding protein (CBP) has a role in the activation of the innate immune response, activation of histones and non-histones through acetylation. It also plays an important role in cAMP-dependent and Wnt signaling. The protein is also involved in modulating the cell cycle, DNA damage repair, ubiquitination and antigen presentation. Mutations in the CBP gene have been associated with Rubinstein-Taybi syndrome. It has also been linked with acute lymphoblastic leukemia.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable