Direkt zum Inhalt
Merck

SAB2500530

Sigma-Aldrich

Anti-IFT88/Polaris antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(e):

Anti-D13S1056E, Anti-HGNC:20606, Anti-Polaris, Anti-TTC10, Anti-Tetratricopeptide repeat domain 10

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

goat

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Speziesreaktivität

mouse, human

Methode(n)

ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... IFT88(8100)

Allgemeine Beschreibung

Intraflagellar transport 88 (IFT88) is a liver tumor suppressor gene. It consists of 824 amino acids and possesses tetratricopeptide repeats.

Immunogen

Peptide with sequence C-KKRIDEDDFADEE from the C Terminus of the protein sequence according to NP_783195.2; NP_006522.2.

Biochem./physiol. Wirkung

Intraflagellar transport 88 (IFT88) is involved in cilia formation. It is linked to polycystic kidney disease. In mitosis, the protein has a crucial role in spindle orientation. IFT88 is downregulated in hepatocellular carcinoma.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Tg737 signaling is required for hypoxia-enhanced invasion and migration of hepatoma cells.
You N
Journal of Experimental & Clinical Cancer Research (2012)
Polaris, a Protein Involved in Left-Right Axis Patterning, Localizes to Basal Bodies and Cilia
Patrick D
Molecular Biology of the Cell (2001)
The cilia protein IFT88 is required for spindle orientation in mitosis.
Delaval B
Nature Cell Biology (2011)
The molecular biology of polycystic kidney disease
Noel S
Pediatric Nephrology (Berlin) (1998)

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