S3321

SUN B8155

≥97% (HPLC), solid

• Synonym(e): 5-[1-[(2-Aminophenyl)imino]ethyl]-1,6-dihydroxy-4-methyl-2(1H)-pyridinone
• Empirische Formel (Hill-System): C₁₄H₁₅N₃O₃
• CAS-Nummer: 345893-91-6
• Molekulargewicht: 273.29
• MDL-Nummer: MFCD08276926
• UNSPSC-Code: 51111800
• PubChem Substanz-ID: 24724606

Eigenschaften

• Assay: ≥97% (HPLC)
• Form: solid
• Löslichkeit: DMSO: ≥5 mg/mL
• Lagertemp.: 2-8°C
• SMILES String: CC1=CC(=O)N(O)C(O)=C1\C(C)=N\c2ccccc2N
• InChI: 1S/C14H15N3O3/c1-8-7-12(18)17(20)14(19)13(8)9(2)16-11-6-4-3-5-10(11)15/h3-7,19-20H,15H2,1-2H3/b16-9+
• InChIKey: SGJLINMLDNLWOS-CXUHLZMHSA-N

Beschreibung

Anwendung

SUN B8155 may be used to study calcitonin-mediated cell signaling.

Biochem./physiol. Wirkung

SUN B8155 is a pyridine derivative that mimics calcitonin, a peptide hormone crucial in maintain the bone homeostasis. It stimulated the formation of cAMP in T47D and UMR106-06 cells expressing calcitonin receptor.

SUN B8155 is a nonpeptide calcitonin receptor agonist.

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H301
• P-Sätze: P301 + P310
• Gefahreneinstufungen: Acute Tox. 3 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Faceshields, Gloves