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RAB0642
Human F3 / Tissue Factor ELISA Kit
Synonym(e):
Coagulation factor III, TF, Thromboplastin, Tissue factor
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96 WELLS
CHF 594.00
CHF 594.00
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96 WELLS
CHF 594.00
About This Item
UNSPSC-Code:
41116158
NACRES:
NA.32
CHF 594.00
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Empfohlene Produkte
Speziesreaktivität
human
Verpackung
kit of 96 wells (12 strips x 8 wells)
Methode(n)
ELISA: suitable
Aufnahme
sample type cell culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 6 pg/mL
standard curve range: 6.14-1500 pg/mL
Nachweisverfahren
colorimetric
Versandbedingung
wet ice
Lagertemp.
−20°C
Angaben zum Gen
human ... F3(2152)
Verwandte Kategorien
Allgemeine Beschreibung
The antibody pair provided in this kit recognizes human Coagulation Factor III/Tissue Factor.
Tissue factor (TF), also known as coagulation factor III (F3), is encoded by the gene mapped to human chromosome 1p21.3.[1] TF has been shown to exist in two forms, namely membrane-bound and soluble TF.[2] The encoded protein contains an extracellular domain (ED), a single transmembrane domain (TD) and short cytoplasmic domain (CD).[3]
Tissue factor (TF), also known as coagulation factor III (F3), is encoded by the gene mapped to human chromosome 1p21.3.[1] TF has been shown to exist in two forms, namely membrane-bound and soluble TF.[2] The encoded protein contains an extracellular domain (ED), a single transmembrane domain (TD) and short cytoplasmic domain (CD).[3]
Anwendung
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem./physiol. Wirkung
Tissue factor (TF) interacts with the zymogen factor VII (VII) and its activated form VIIa, and initiates blood coagulation protease cascade.[2][4] The encoded protein is involved in the pathogenesis of cardiovascular diseases, such as hypertension, atherosclerosis, acute coronary syndrome and restenosis. Thus, it is considered to be a potential therapeutic target for cardiovascular diseases.[2]
Signalwort
Warning
H-Sätze
P-Sätze
Gefahreneinstufungen
Met. Corr. 1
Lagerklassenschlüssel
8A - Combustible corrosive hazardous materials
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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Christoph Schliemann et al.
Cancers, 12(6) (2020-06-11)
Aminopeptidase N (CD13) is present on tumor vasculature cells and some tumor cells. Truncated tissue factor (tTF) with a C-terminal NGR-peptide (tTF-NGR) binds to CD13 and causes tumor vascular thrombosis with infarction. We treated 17 patients with advanced cancer beyond
Gordana Kocic et al.
Cancers, 12(10) (2020-10-18)
Balkan endemic nephropathy (BEN) is a chronic tubulointerstitial disease frequently accompanied by urothelial carcinoma (UC). In light of the increased UC incidence and the markers observed in BEN patients with developed UC, the aim of the current case-control study is
Role of tissue factor in metastasis: functions of the cytoplasmic and extracellular domains of the molecule.
Bromberg M E, et al.
Thrombosis and Haemostasis, 82(01), 88-92 (1999)
Bin Jiang et al.
Biotechnology and bioengineering, 114(10), 2371-2378 (2017-05-26)
The clinical translation of cell-based therapeutics often requires highly sensitive, non-invasive imaging tools to assess cell function and distribution in vivo. The objective of this research was to determine whether human Sodium-Iodide Symporter (hNIS) ectopic expression in endothelial cells (ECs)
Saika Manzoor et al.
Scientific reports, 9(1), 10182-10182 (2019-07-17)
Polycystic ovarian syndrome (PCOS) is a multispectral disorder requiring lifelong management. Its pathophysiology is still being explored which makes its treatment options restrained. Present study explores impact of oral contraceptive mode of treatment on metabolic, hormonal, inflammation and coagulation profile
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