Direkt zum Inhalt
Merck

RAB0629

Sigma-Aldrich

Human GDF2 / Growth/Differentiation Factor 2 ELISA Kit

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise

Größe auswählen

96 WELLS
CHF 594.00

CHF 594.00


Voraussichtliches Versanddatum19. Mai 2025



Größe auswählen

Ansicht ändern
96 WELLS
CHF 594.00

About This Item

UNSPSC-Code:
41116158
NACRES:
NA.32

CHF 594.00


Voraussichtliches Versanddatum19. Mai 2025


Speziesreaktivität

human

Verpackung

kit of 96 wells (12 strips x 8 wells)

Methode(n)

ELISA: suitable

Aufnahme

sample type plasma
sample type cell culture supernatant(s)
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 32 pg/mL
standard curve range: 32.77-8000 pg/mL

Nachweisverfahren

colorimetric

Versandbedingung

wet ice

Lagertemp.

−20°C

Angaben zum Gen

human ... GDF2(2658)

Allgemeine Beschreibung

The growth differentiation factor 2 (GDF2) gene encodes for bone morphogenic protein 9 (BMP9).[1] GDF2, also known as BMP9, belongs to the BMP family.[2] The GDF2 gene is mapped on the human chromosome at 10q11.22.[3] GDF2/BMP9 protein regulates angiogenesis, modulating tumorigenesis, inhibiting hepatic glucose production, and maintaining basal forebrain cholinergic neurons.[2] It is implicated in the pathogenesis of pulmonary arterial hypertension.[2] Mutations in the GDF2 gene are associated with hereditary hemorrhagic telangiectasia (HHT), an autosomal dominant vascular disorder.[1] The antibody pair provided in this kit recognizes human growth/differentiation factor 2.

Anwendung

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Kit-Komponenten auch einzeln erhältlich

Produkt-Nr.
Beschreibung
SDB

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDB

  • RABSTOP3ELISA Stop Solution (Item I)SDB

  • RABWASH420X Wash Buffer (Item B)SDB

Piktogramme

Corrosion

Signalwort

Warning

H-Sätze

P-Sätze

Gefahreneinstufungen

Met. Corr. 1

Lagerklassenschlüssel

8A - Combustible corrosive hazardous materials

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

Die passende Version wird nicht angezeigt?

Wenn Sie eine bestimmte Version benötigen, können Sie anhand der Lot- oder Chargennummer nach einem spezifischen Zertifikat suchen.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Wei Liu et al.
Genes & diseases, 7(2), 235-244 (2020-03-28)
Bone morphogenetic protein 9 (BMP9) (or GDF2) was originally identified from fetal mouse liver cDNA libraries. Emerging evidence indicates BMP9 exerts diverse and pleiotropic functions during postnatal development and in maintaining tissue homeostasis. However, the expression landscape of BMP9 signaling
Felicia Hernandez et al.
Human genome variation, 2, 15040-15040 (2015-01-01)
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular disorder caused by mutations in ENG, ACVRL1 and SMAD4, which function in regulating the transforming growth factor beta and bone morphogenetic protein signaling pathways. Symptoms of HHT can be present in
Z Yang et al.
Science advances, 6(48) (2020-11-29)
Obesity drives the development of nonalcoholic fatty liver disease (NAFLD) characterized by hepatic steatosis. Several bone morphogenetic proteins (BMPs) except BMP9 were reported related to metabolic syndrome. This study demonstrates that liver cytokine BMP9 is decreased in the liver and
Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients.
Saus, et al.
Journal of Psychiatric Research, 44, 971-978 (2018)
Yan-Man Zhou et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 35(5), 978-993 (2020-01-09)
Bone remodeling is dynamic and is tightly regulated through bone resorption dominated by osteoclasts and bone formation dominated by osteoblasts. Imbalances in this process can cause various pathological conditions, such as osteoporosis. Bone morphogenetic protein 9 (BMP9), a biomolecule produced

Questions

Reviews

No rating value

Active Filters

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.